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Herpes zoster: geen roos zonder doorn

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Opstelten W. Herpes zoster: geen roos zonder doorn. Huisarts Wet 2006;49(12):606-610.Herpes zoster (gordelroos) is meestal een onschuldige aandoening. Sommige patiënten houden echter last van langdurige pijn, men noemt dit postherpetische neuralgie. Nooit eerder is in de huisartsenpraktijk systematisch onderzocht welke factoren het risico op deze complicatie bepalen. Weliswaar hebben anesthesiologen geadviseerd om bij oudere gordelroospatiënten een eenmalige ruggenprik met steroïden en analgetica te overwegen ter preventie van postherpetische neuralgie, maar de effectiviteit van deze interventie is niet bewezen. Het PINE-onderzoek, waaraan honderden huisartsen meewerkten, had tot doel deze effectiviteit te onderzoeken. De resultaten geven de huisarts nieuwe informatie over de prognose en behandeling van gordelroos.

Abstract

Opstelten W. Herpes zoster: geen roos zonder doorn. Huisarts Wet 2006;49(12):606-10.Herpes zoster (shingles) is usually a benign, self-limiting disease. However, some patients are afflicted with protracted pain, so-called postherpetic neuralgia. The factors contributing to the risk of this complication have never been studied in general practice. Although anaesthesiologists have advised that a single epidural injection with and steroids and analgesics should be considered as a preventive measure against postherpetic neuralgia, the effectiveness of the intervention has never been demonstrated. The PINE study, on which hundreds of GPs collaborated, was intended to quantify the effectiveness of the measure. The results provide the GP with new information on prognosis and therapy in shingles.

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    Wim Opstelten

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  1. Wim Opstelten
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Correspondence to Wim Opstelten.

Additional information

Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Postbus 85060, 3500 AB Utrecht: dr. W. Opstelten, huisarts.

Mogelijke belangenverstrengeling: niets aangegeven.

Herpes zoster is fascinating because it arrives unpredictably,

is readily diagnosed – a rare pleasure for most of us – and

difficult to explain.

Sir Robert Edgar Hope-Simpson

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Opstelten, W. Herpes zoster: geen roos zonder doorn. HUWE 49, 863–868 (2006). https://doi.org/10.1007/BF03084967

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