Abstract
Op dit moment zijn er in Nederland naar schatting 250.0000 mensen met dementie, van wie 60 á 70% de ziekte van Alzheimer heeft. De prevalentie zal, gezien de vergrijzing, in de toekomst sterk toenemen. Honderd jaar na de ontdekking van de ziekte zijn de onderliggende moleculaire mechanismen die leiden tot het geleidelijke verlies van cognitieve functies, zoals het geheugen, nog voor het grootste gedeelte onbekend. Op dit moment bestaat er geen werkzame therapie.
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Mw. dr. M.Mulder, biologe, Universiteit Maastricht, Afdeling Basale Neurowetenschappen, Instituut Hersenen & Gedrag, EURON, Postbus 616, 6200 MD Maastricht,
Drs. T. Vanmierlo, moleculair bioloog, Universiteit Maastricht, euron
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Mulder, M., van Mierlo, T. Cholesterol: nieuw therapeutisch target bij de ziekte van Alzheimer?. NEPR 11, 64–68 (2007). https://doi.org/10.1007/BF03079128
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DOI: https://doi.org/10.1007/BF03079128