Abstract
Het onderzoek naar de effecten van psychoactieve stoffen op de rijvaardigheid is van groot belang omdat steeds meer verkeersdeelnemers van die stoffen gebruikmaken. Er zijn verscheidene methoden om de rijvaardigheid te bepalen, waaronder laboratoriumtesten, simulators en een rijvaardigheidstest in het normale verkeer. De laatstgenoemde blijkt het normale rijden het best te repliceren. In de 100-km-rijvaardigheidstest worden proefpersonen geïnstrueerd het voertuig te besturen met een constante laterale positie en snelheid. De mate van slingeren van de auto, de Standaard Deviatie van de Laterale Positie (sdlp), is de belangrijkste maat die de voertuigbeheersing (en dus rijvaardigheid) weergeeft.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literatuur
Brookhuis K.A., Volkerts E.R., O'Hanlon J.F. Repeated dose effects of lormetazepam and flurazepam upon driving performance. Eur J Clin Pharmacol 1990, 38:1-5. (studie 5).
O'Hanlon J.F., Haak T.W., Blauw G.J., Riemersma J.B.J. Diazepam impairs lateral position control in highway driving. Science 1982, 217:79-81.
O'Hanlon J.F. Driving under the influence of drugs: rationale for, and application of, a new test. Br J Clin Pharmacol 1984, 18:121S-129S. (studies 1 en 2).
O'Hanlon J.F., Volkerts E.R. Hypnotics and actual driving ability. Acta Psychiatr Scand 1986, 74 (suppl 332):95-104. (studie 4).
Laar M.W. van, Volkerts E.R., Verbaten M.N. Subchronic effects of the gaba-agonist lorazepam and the 5-HT2a/2c antagonist ritanserin on driving performance, slow wave sleep and daytime sleepiness in healthy volunteers. Psychopharmacol 2001, 154:189-197.
Michon J.A. A critical view of driver behavior models. What do we know, what should we do? In: Evans L., Schwing R.C. (eds.). Human behavior and traffic safety. New York, Plenum Press, 1985.
Ramaekers J.G. Antidepressants and driving impairment: empirical evidence from a standard on-the-road test. J Clin Psychiatry 2003, 64:20-29.
Ranney T.A. Models of driving behavior: a review of their evolution. Accid Anal and Prev 1994, 26: 733-750.
Rasmussen J. The definition of human error and a taxonomy for technical system design. In: Rasmussen J. Duncan K., Leplat J. (eds.). New technology and human error. Chichester, U.K., Wiley, 1987.
Vermeeren A., O'Hanlon J.F., DeClerck A.C., et al. Acute effects of zolpidem and flunitrazepam on sleep, memory and driving performance, compared to those of partial sleep deprivation and placebo. Acta Therapeutica 1995, 21:47-64. (studie 7).
Vermeeren A., Danjou P.E., O'Hanlon J.F. Residual effects of evening and middle-of-the-night administration of zaleplon 10 and 20 mg on memory and actual driving performance. Hum Psychopharmacol Clin Exp 1998; 13: S98-S107. (studie 8).
Vermeeren A., Riedel W.J., van Boxtel M.P.J., et al. Differential residual effects of zaleplon and zopiclone on actual driving: a comparison with a low dose of ethanol. Sleep 2002, 25:224-231. (studie 9).
Verster J.C. Measurement of the effects of psychoactive drugs on driving ability and related psychological processes. Thesis. Utrecht, The Netherlands, 2002.
Verster J.C., Volkerts E.R., Schreuder A.H.C.M.L., Eijken E.J.E., Van Heuckelum J.H.G., Veldhuijzen D.S., Verbaten M.N., Patat A., Paty I. Residual effects of middle-of-the-night administration of zaleplon and zolpidem on driving ability, memory functions and psychomotor performance. Journal of Clinical Psychopharmacology, 2002a, 22:576-583. (studie 10).
Verster J.C., Volkerts E.R., Verbaten M.N. Effects of alprazolam on driving ability, memory functioning and psychomotor performance: a randomized, placebo-controlled study. Neuropsychopharmacology 2002b, 27: 260-269.
Verster J.C., Verbaten M.N., Volkerts E.R. Next-day residual effects of sleep medicine on driving ability: a review of the literature. In: Lader, Pandi-Perumal, Cardinali (Eds.): Sleep and Sleep Disorders: a Neuropsychopharmacological Approach. Landes Press, 2004a, In press.
Verster J.C., Volkerts E.R. cme Review: Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic. Ann Allergy Asthma Immunol 2004b, 92: 294-304.
Volkerts E.R., Louwerens J.W., Gloerich A.B.M., et al. Zopiclone's residual effect upon actual driving performance versus those of nitrazepam and flunitrazepam. vsc, Report 84-10, Traffic Research Centre, Groningen, The Netherlands, 1984. (studie 3).
Volkerts E.R., van Laar M.W., van Willigenburg A.P.P., et al. A comparative study of on-the-road and simulated driving performance after nocturnal treatment with lormetazepam 1 mg and oxazepam 50 mg. Hum Psychopharmacol 1992; 7:297-309. (studie 6).
Author information
Authors and Affiliations
Corresponding author
Additional information
J. C. Verster, Universiteit Utrecht, Utrecht Institute for Pharmaceutical Sciences, Afdeling Psychofarmacologie, Postbus 80082, 3508 TB, Utrecht
Mw. drs. D. Velduijzen, psychofarmacologe;
Dr. E.R. Volkerts, psychofarmacoloog.
Rights and permissions
About this article
Cite this article
Verster, J., Veldhuijzen, D. & Volkerts, E. Het meten van rijvaardigheid in het normale verkeer: de effecten van hypnotica. NEPR 8, 34–38 (2004). https://doi.org/10.1007/BF03078996
Issue Date:
DOI: https://doi.org/10.1007/BF03078996