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Craving: tussen de biologie en psychologie van alcoholafhankelijkheid

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Neuropraxis

Abstract

Alcoholcraving is het vaak sterke en soms overweldigende verlangen om te drinken. Dit fenomeen speelt een belangrijke rol bij de overgang van gecontroleerd drinken naar alcoholafhankelijkheid, de mechanismen die ten grondslag liggen aan terugval en de behandeling van verslaving. In dit artikel wordt een psychobiologisch etiologisch model gepresenteerd, waarbij voor drie verschillende vormen van craving de mogelijke biologische en psychologische wortels worden beschreven.

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Literatuur

  • Anton R.F., Moak D.H. & Latham P.K. (1996). The Obsessive Compulsive Drinking Scale: a self-rated instrument for the quantification of thoughts about alcohol and drinking behaviour. Alcoholism Clinical and Experimental Research 19, 92-99.

    Google Scholar 

  • Breiter H.C., Rauch S.L., Kwong K.K. e.a. (1996). Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. Archives of General Psychiatry 53, 595-606.

    Google Scholar 

  • Buydens-Branchey L., Branchey M., Fergeson P. e.a. (1997). Hormonal, psychological, and alcohol craving changes after m-Chlorophenylpiperazine administration in alcoholics. Alcoholism Clinical and Experimental Research 21, 220-227.

    Google Scholar 

  • Chick J., Howlett H., Morgan M.Y. & Ritson B. (2000). United Kingdom Multicenter Acamprosate Study (ukmas): a 6-month prospective study of acamprosate versus placebo in preventing relapse after withdrawal from alcohol. Alcohol & Alcoholism 35, 176-187.

    Google Scholar 

  • Cloninger C.R. (1987). Neurogenetic adaptive mechanisms in alcoholism. Science 236, 410-436.

    Google Scholar 

  • Conrod P.J., Pihl R.O. & Vassileva J. (1998). Differential sensitivity to alcohol reinforcement in groups of men at risk for distinct alcoholism subtypes. Alcoholism Clinical and Experimental Research 22, 585-597.

    Google Scholar 

  • Cooney N.L., Litt M.D., Morse P.A. e.a. (1997). Alcohol cue reactivity, negative-mood reactivity, and relapse in treated alcoholic men. Journal of Abnormal Psychology 106, 243-250.

    Google Scholar 

  • Cornelius J.R., Salloum I.M., Ehller J.G., e.a. (1997). Fluoxetine in depressed alcoholics: a double-blind, placebo-controlled trial. Archives of General Psychiatry 54, 700-705.

    Google Scholar 

  • Cowley D.S., Roy-Byrne P.P., Greenblatt D.J., e.a. (1996). Effect of diazepam on plasma g-aminobutyric acid in sons of alcoholic fathers. Alcoholism Clinical and Experimental Research 20, 343-347.

    Google Scholar 

  • Depue R.A., Luciana M., Arbisi P. e.a. (1994). Dopamine and the structure of personality: relation of agonist-induced dopamine activity to positive emotionality. Journal of Personality and Social Personality 67, 485-498.

    Google Scholar 

  • Gerra G., Caccavari R., Delsignore R. e.a. (1992). Effects of fluoxetine and Ca-Acetyl-Homotaurniate on alcohol intake in familial and nonfamilial alcoholic patients. Current Therapeutic Research 52, 291-295.

    Google Scholar 

  • Gerra G., Ferri M., Zaimovic A. e.a. (1998). GABAergic function in detoxified heroin addicts: relationship to anxiety disorders. Psychiatry Research 77, 89-96.

    Google Scholar 

  • Gianoulakis C. (1996). Implications of endogenous opioids and dopamine in alcoholism: human and basic science studies. Alcohol & Alcoholism 31, 33-42.

    Google Scholar 

  • Goodman W.K., Price L.H., Delgado P.L. e.a. (1990). Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorders. Archives of General Psychiatry 47, 577-585.

    Google Scholar 

  • Goodwin D.W. (1985). Alcoholics and genetics: the sins of the fathers. Archives of General Psychiatry 42, 171-174.

    Google Scholar 

  • Grant S., London E.D., Newlin D.B. e.a. (1996). Activation of memory circuits during cue-elicited cocaine craving. Proceedings of the National Academy of Sciences USA 93, 12040-12045.

    Google Scholar 

  • Hill S.Y., Locke J., Zezza N. e.a. (1998). Genetic association between reduced P300 amplitude and the drd2 dopamine receptor A1 allele in children at high risk for alcoholism. Biological Psychiatry 43, 40-51.

    Google Scholar 

  • Hollander E., DeCaria C.M., Nitescu A. e.a. (1992). Serotonergic function in obsessive-compulsive disorder. Archives of General Psychiatry 49, 21-28.

    Google Scholar 

  • King A.C., Volpicelli J.R., Frazer A. & O'Brien C.P. (1997). Effect of naltrexone on subjective alcohol response in subjects at high and low risk for future alcohol dependence. Psychopharmacology 129, 15-22.

    Google Scholar 

  • Koeter M.W.J., Brink W. van den & Hartgers C. (1995). Cloninger's type I and II alcoholics among treated alcoholics: prevalence and validity of the construct. European Addiction Research 1, 187-193.

    Google Scholar 

  • Lesch O.M. & Walter H. (1996). Subtypes of alcoholism and their role in therapy. Alcohol & Alcoholism 31 (supplement), 63-67.

    Google Scholar 

  • Maas L.C., Lukas S.E., Kaufman M.J. e.a. (1998). Functional magnetic resonance imaging of human brain activation during cue-induced cocaine craving. American Journal of Psychiatry 155, 124-126.

    Google Scholar 

  • Monti P.M., Rohsenow D.J., Hutchison K.E. e.a. (1999). Naltrexone's effect on cue-elicited craving among alcoholics in treatment. Alcoholism Clinical and Experimental Research 23, 1386-1394.

    Google Scholar 

  • Naranjo C.A., Sellers E.M., Jullivan J.T. e.a. (1987). The serotonin uptake inhibitor citalopram attenuates ethanol intake. Clinical Pharmacological Therapy 41, 266-274.

    Google Scholar 

  • Niaura R.S., Rohsenow D.J., Binkoff J.A. e.a. (1988). Relevance of cue reactivity to understanding alcohol and smoking relapse. Journal of Abnormal Psychology 97, 133-152.

    Google Scholar 

  • Praag H.M. van (1990). Two-tier diagnosing in psychiatry. Psychiatry Research 34, 1-11.

    Google Scholar 

  • Robinson T.E. & Berridge K.C. (1993). The neural basis of craving: an incentive-sensitization theory of addiction. Brain Research Review 18, 247-291.

    Google Scholar 

  • Samson H.H. & Harris R.A. (1992). The neurobiology of alcohol abuse. Trends in Pharmacological Sciences 13, 206-211.

    Google Scholar 

  • Siever L.J. & Davis K.L. (1991). A psychobiological perspective on the personality disorders. American Journal of Psychiatry 148, 1647-1658.

    Google Scholar 

  • Spanagel R. & Zieglgänsberger W. (1997). Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes. Trends in Pharmacological Sciences 18, 54-59.

    Google Scholar 

  • Tiffany S.T. (1990). A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes. Psychological Review 97, 147-168.

    Google Scholar 

  • Tsai G.E., Ragan P., Chang R. e.a. (1998). Increased glutamatergic neurotransmission and oxidative stress after alcohol withdrawal. American Journal of Psychiatry 155, 726-732.

    Google Scholar 

  • Verheul R., Brink W. van den & Geerlings P.J. (1999). A three-pathway psychobiological model of craving for alcohol. Alcohol & Alcoholism 34, 197-222.

    Google Scholar 

  • Verkes R.J. (1998). The low serotonin syndrome in recurrent suicidal behaviour (dissertation). Universiteit Leiden.

  • Volpicelli J.R. (1987). Uncontrollable events and alcohol drinking. British Journal of Addiction 82, 381-392.

    Google Scholar 

  • Wand G.S., Mangold D., El-Deiry S. e.a. (1998). Family history of alcoholism and hypothalamic opoidergic activity. Archives of General Psychiatry 55, 1114-1119.

    Google Scholar 

  • World Health Organization (1992). De icd-10 Classificatie van psychische stoornissen en gedragsstoornissen: klinische beschrijvingen en diagnostische richtlijnen. Lisse, Swets & Zeitlinger.

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Verheul, R. Craving: tussen de biologie en psychologie van alcoholafhankelijkheid. NEPR 4, 123–129 (2000). https://doi.org/10.1007/BF03078980

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