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‘Short bowel’-syndroom: citrulline als parameter van het absorptievermogenvan de enterocyt

  • Casuïstische mededelingen
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Tijdschrift voor kindergeneeskunde

Summary

Determination when patients with short bowel syndrome grow independently of parenteral nutrition remains a large clinical problem. A possible parameter with positive predictive value for enteric function could be plasma citrulline. Citrulline is a non-protein amino acid, produced by the enterocyte. To support this hypothesis, we report of two patients with short bowel syndrome in whom this marker has been determined during the course of their disease.

Samenvatting

Het is moeilijk te bepalen wanneer de adaptatie van het darmepitheel bij kinderen met het ‘short bowel’-syndroom voltooid is, zodanig dat zij onafhankelijk van parenterale voeding kunnen leven en groeien. Een mogelijke parameter met een positieve voorspellende waarde voor darmfunctie is het plasma citrulline. Citrulline is een aminozuur geproduceerd door de enterocyt. Om deze hypothese te ondersteunen, rapporteren wij over twee patiënten met een ‘short bowel’-syndroom, waarbij deze parameter in het verloop van hun ziektebeeld werd bepaald.

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  1. www.bsl.nl/shop/tydschrift-vkindergeneeskunde-0376-7442.html

    W. Onland

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  1. W. Onland
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  2. Chr. Sleeboom
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  3. D. C. Aronson
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Corresponding author

Correspondence to W. Onland.

Additional information

W. Onland, arts-assistent, afdeling Kindergeneeskunde; Chr. Sleeboom, dr. D.C. Aronson, Kinderchirurgisch Centrum Amsterdam, Emma Kinderziekenhuis, amc, Amsterdam.Correspondentieadres: Wes Onland, afdeling Kindergeneeskunde, Emma Kinderziekenhuis, Academisch Medisch Centrum, Postbus 22660, 1100 DD Amsterdam, tel: 020-5669111, fax: 020-5664440

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Onland, W., Sleeboom, C. & Aronson, D.C. ‘Short bowel’-syndroom: citrulline als parameter van het absorptievermogenvan de enterocyt. KIND 73, 175–178 (2005). https://doi.org/10.1007/BF03061572

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  • DOI: https://doi.org/10.1007/BF03061572

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