Summary
Acute life-threatening diseases that coincide with a systemic inflammatory response such as septic shock may lead to serious organ dysfunction. Often this occurs very early in the course of the disease, the ‘golden hours’. There is sufficient support from the literature that early recognition of a imminent circulatory insufficiency and aggressive early goal directed therapy are essential for a good outcome of these patients.
Samenvatting
Acute ernstige aandoeningen die gepaard gaan met een systemische inflammatoire reactie zoals septische shock, kunnen leiden tot ernstig orgaanfalen. Het ontstaan van dergelijk kritisch orgaanfalen gebeurt vaak in de eerste uren, de ‘gouden uren’. Er is voldoende ondersteuning in de literatuur dat tijdige herkenning van de dreigende circulatoire insufficiëntie en in de vroegst mogelijke fase instellen van een agressieve, direct op resultaat gerichte behandeling essentieel zijn voor een goede uitkomst van deze patiënten.
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Dr. J.B.M. van Woensel, kinderarts-intensivist en dr. A.P. Bos, kinderarts-intensivist, afdeling Intensive Care Kinderen, Emma Kinderziekenhuis AMC, Amsterdam.
Correspondentieadres: J.B.M. van Woensel, afdeling Intensive Care Kinderen, Emma Kinderziekenhuis AMC, Postbus 22660, 1100 DD Amsterdam, tel: 020-5665769, fax: 020-6919338.
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van Woensel, J.B.M., Bos, A.P. Vroege, op direct resultaat gerichte behandeling van acute circulatoire insufficiëntie. KIND 72, 159–162 (2004). https://doi.org/10.1007/BF03061507
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DOI: https://doi.org/10.1007/BF03061507