Riassunto
Gli AA. riferiscono i risultati ottenuti dall’applicazione di un metodo radioimmunologico di dosaggio dell’angiotensina I quale indice di attività renino-plasmatica. Vengono sottolineate 1a fedeltà del metodo e la sua riproducibilità. Viene inoltre indicato un particolare programma di calcolo che si basa sull’utilizzazione di un elaboratore elettronico.
Summary
The results obtained from the application of a radioimmunoassay method of angiotensin I for the indication of renin-plasmatic activity are reported. The method is accurate and reproducible, and a special computer program is used to calculate the results. Requests for reprints should be addressed to:
References
Boyd G. W., Adamson A.R., Fitz A.B., Peart W. S.: Radioimmunoassay Determination of Plasma Renin Activity - Lancet1, 213, 1969.
Deodhar S.D.: Immunologic Production of Anti-Angiotensin. I. Preparation of Angiotensin-Protein Complex Antigen - J. exp. Med.111, 419, 1960.
Goodfriend T. L., Levine L., Fasman G.D.: Antibodies to Bradykinin and Angiotensin: Use of Carbodiimides in Immunology - Science144, 1344, 1964.
Haber E.: Recent Developments in Pathophysiologic Studies of the Renin-Angiotensin System - New Engl. J. Med.280, 148, 1969.
Haber E., Koerner T., Page L. B.: Immunoassay for Angiotensin I and its Application to Determination of Renin Activity - Circulation38, (suppl. 6), 91, 1968.
Haber E., Koerner T., Page L. B., Kliman B., Purnode A.: Application of a Radioimmunoassay for Angiotensin I to the Physiologic Measurements of Plasma Renin Activity in Normal Human Subjects - J. clin. Endocr.29, 1349, 1969.
Haber E., Page L. B., Jacoby G.A.: Synthesis of Antigenic Branch-Chain Copolymers of Angiotensin and Poly-L-Lysine - Biochemistry4, 693, 1965.
Hunter W. M., Greenwood F.G.: Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity- Nature (Lond.)194, 495, 1962.
Sen S., Smeby R. R., Bumpus F.M.: Isolation of Phospholipid Renin Inhibitor from Kidney -Biochemistry6, 1572, 1967.
Stason W. B., Vallotton M., Haber E.: Biochim. biophys. Acta (Amst.)133, 582, 1967. Quoted by Haber e Coll.6
Vallotton M., Page L. B., Haber E.: Radioimmunoassay of Angiotensin in Human Plasma -Nature (Lond.)215, 714, 1967.
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Bagni, B., Gilli, P., Imbimbo, G.C. et al. Determinazione dell’attività reninica plasmatica mediante radioimmunodosaggio dell’angiotensina I. La Ricerca Clin. Lab. 1, 399–412 (1971). https://doi.org/10.1007/BF03054469
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DOI: https://doi.org/10.1007/BF03054469