Trace element nutrition of the silkwormBombyx mori L.

II. Relationship between cobalt, vitamin B12, benzimidazole and purines
  • S. Sridhara
  • J. V. Bhat


Benzimidazole is toxic to silkworms due to its antagonistic action to purines. Cobalt and copper possess the capacity to reverse its toxicity because of their ability to form complexes with benzimidazole. For reasons unknown cobalt exerts a favourable effect in its free form rather than in the vitamin form on the insect growth.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bheemeswar, B... “Biochemical studies on the silkwormBombyx mori L.,”Ph.D. Thesis, Univ. of Bombay, India, 1954.Google Scholar
  2. Garibaldi, J. A., Ijichi, K., Snell, N. S. and Lewis, J. C. “Bacillus megatherium for biosynthesis of cobalamin,”Ind. Eng. Chem., 1953,45, 838–46.CrossRefGoogle Scholar
  3. Gillespie, H. B., Engelman, M. and Graff, S. “Benzimidazoles and benzotriazoles as growth antagonists,”J. Am. Chem. Soc., 1954,76, 3531–33.CrossRefGoogle Scholar
  4. Konecky, M. S. and Mitlin, N. “Chemical impairment of development in houseflies,”J. Econ. Entomol., 1955,48, 219–20.Google Scholar
  5. Levinson, Z. H. and Bergmann, E. D. “Vitamin deficiencies in the housefly produced by antivitamins,”J. Insect. Physiol., 1959,3, 293–305.CrossRefGoogle Scholar
  6. Slonimski, P. P. and Perrodin, G. “Inhibition of the growth of yeast by benzimidazole. Mechanism of the reversion of the inhibition,”Ann. Inst. Pasteur., 1954,87, 404–12.Google Scholar
  7. Sridhara, S. and Bhat, J. V. .. “Trace element nutrition of the silkwormBombyx mori L. I. Effect of trace elements,”Proc. Ind. Acad. Sci., 1966.Google Scholar
  8. Takahashi, J... “Vitamin B12 in silkworms—II,”Nippon Nogei-Kagaku Kaishi, 1955,29, 711–15.Google Scholar
  9. —————.. “Vitamin B12 in silkworms—III,” Ibid., 1956,30, 563–65.Google Scholar

Copyright information

© Indian Academy of Sciences 1966

Authors and Affiliations

  • S. Sridhara
    • 1
  • J. V. Bhat
    • 1
  1. 1.Fermentation Technology LaboratoryIndian Institute of ScienceBangalore-12India

Personalised recommendations