Summary
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1.
The damaging effects of inhalation of beryl dust on guinea-pigs lung and other organs are studied using Hilton and Kettle technique.
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2.
It has been shown that beryl produces in the lungs chemical pneumonitis at the onset and later leads to marked atrophic emphysema. No evidence of fibriosis or silicious nodule formation was noted.
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3.
Other organs like liver and kidney showed signs of damage, but adrenal cortex showed definite pathological changes in the zona glomerulosa and zona fasciculata with the duration of the experiment.
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4.
The importance of concurrent study of the morphological chemistry of the dust in relation to its role in the production of silicosis is emphasised as such a method if followed by workers in this field may render a rational approach to the fundamental problem of silicosis.
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Communicated by Dr. K. V. Giri,f.a.sc.
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Ramaswamy, A.S., Rao, R.R. Experimental pneumokoniosis caused by beryl dust in guinea-pigs. Proc. Indian Acad. Sci. 37, 158–165 (1953). https://doi.org/10.1007/BF03050477
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DOI: https://doi.org/10.1007/BF03050477