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A blood anticoagulant factor from the latex ofCarica papaya

Part I. Purification and general properties

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Proceedings / Indian Academy of Sciences

Summary

A factor capable of effectively inhibiting the process of coagulation of plasma as well as whole blood has been isolated from the latex ofCarica papaya. Attempts were made at purification of the factor by adsorption and fractional precipitation with organic solvents. A comparatively pure product was obtained by cold acetone fractionation at a final concentration of 42 to 48%. It was found that there was no correlation between the residual proteolytic activity and the anticoagulant property of the factor. Some of the general properties of the anticoagulant factor have also been studied.

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Authors and Affiliations

  1. Department of Biochemistry, Indian Institute of Science, Bangalore, India

    N. C. Pillai, C. S. Vaidyanathan & K. V. Giri

Authors
  1. N. C. Pillai
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  2. C. S. Vaidyanathan
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  3. K. V. Giri
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Pillai, N.C., Vaidyanathan, C.S. & Giri, K.V. A blood anticoagulant factor from the latex ofCarica papaya . Proc. Indian Acad. Sci. 42, 316–324 (1955). https://doi.org/10.1007/BF03050210

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  • DOI: https://doi.org/10.1007/BF03050210

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