Summary
1. Small concentrations of methyl, ethyl, propyl and butyl alcohols cause active relaxation of the contractile mechanism of unstriated muscle; larger concentrations produce contraction.
2. Copper sulphate, mercuric chloride, carbolic acid and formalin have similar effects.
3. The above substances are known to produce denaturation of proteins in small concentrations and coagulation in higher concentrations; it therefore appears that active relaxation is akin to denaturation and contraction to coagulation of proteins.
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References
Singh, S. I. and Singh, I...Curr. Sci., 1954a,23, 126.
—————..Proc. Ind. Acad. Sci., 1954b,40, 125.
—————.. Ibid., 1954c,40, 145.
—————.. Ibid., 1951,33, 165.
—————.. Ibid., 1949,30, 270.
—————.. Ibid., 1950,32, 12.
----- ..Ibid., 1955.
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Singh, S.I., Singh, I. Further observations on the relation between denaturation of proteins and relaxation of unstriated muscle. Proc. Indian Acad. Sci. 41, 183–187 (1955). https://doi.org/10.1007/BF03050089
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DOI: https://doi.org/10.1007/BF03050089