Summary
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(1)
Infantile Cirrhosis is a disease found to a greater extent amongst the children of the vegetarian and to a lesser extent in the non-vegetarian families. The disease is not met with amongst the Muslims and the Europeans.
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(2)
There are two factors in the ætiology of the disease; cow’s milk andB. coli infection. Cow’s milk brings about the predisposing factor—viz., gastro-intestinal disorder and devitalization of the liver—andB. coli the cirrhotic changes in the liver.
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(3)
The pathological condition of the blood indicates an increase of leucocytes with lymphocytes predominating. The blood sugar is low and blood urea is normal.
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(4)
Jaundice is present in a few cases only and this complication arises as a result of obstruction to bile capillaries in later stages of the disease.
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(5)
The morbid anatomy of the liver presents a picture ofportal cirrhosis. The clinical condition of the disease as well as the histological features of the liver fulfil the criteria of portal or Lænnec’s cirrhosis.
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(6)
It is suggested that the nomenclature of the disease should be ‘Infantile Cirrhosis’ and not ‘Infantile biliary Cirrhosis’.
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An erratum to this article is available at http://dx.doi.org/10.1007/BF03051470.
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Rao, P.K. Infantile Cirrhosis of the liver. Proc. Indian Acad. Sci. 14, 310–338 (1941). https://doi.org/10.1007/BF03048516
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DOI: https://doi.org/10.1007/BF03048516