Abstract
A case of bilateral moderate sensori-neural hearing loss due to oral administration of ciprofloxacin is reported. To our best of knowledge so far ciprofloxacin associated hearing loss has not been reported. The hearing loss recovered gradually in a period of 4–5 weeks following withdrawal of the drug. Traditionally, the known side effects of ciprofloxacin are not serious in nature and reversible which is true of the hearing loss in the present case. Awareness of this side effect is of paramount importance and further reports are awaited in this regard.
References
Arcieri, G.M., Becker, N., Esposito, B., Griffith, E., Heyd, A., Neumann, C., O’Brien, B., Schacht, P., (1989): Safety of Intravenous Ciprofloxacin. The American Journal of Medicine, 87 (Suppl 5A) 92S-97S.
Brownlee, R.E., Hulka, G.F., Prazma, J., Pillsbury III, H.C., (1992): Ciprofloxacin use as a topical otic preparation. Archives of Otolaryngology-Head and Neck Surgery 118; 392–396.
Chodosh, S., Tuck, J., Stottmeier, K.D., Pizzuto, D. (1989): Comparison of Ciprofloxacin with Ampicillin in Acute Infectious Exacerbations of Chronic Bronchitis. A double blind crossover study. The American Journal of Medicine 87 (Suppl. 5A) 107S-112S.
Levenson, M.J., Parisier, S.C., Dolitsky, J., Bindra, G., (1991): Ciprofloxacin: Drug of choice in the treatrment of Malignant External Otitis. Laryngoscope, 101; 821–824.
Nomura, M., Yamada, M., Yamamura, H., Kazimura, T., Takayama, S., (1992): Ophthalmotoxicity and Ototoxicity of the new quinolone antibacterial agent Levofloxacin in Long Evans rate. Journal of Laryngology & Otology (Abstract selection) 106: 937.
Schacht, P., Arcieri, G., Hullmann, R., (1989): Safety of Oral Ciprofloxacin. An update based on clinical trial results. The American Journal of Medicine, 87 (Suppl. 5A) 98S-102S.
Schluter, G., (1989): Ciprofloxacin: Toxicologic Evaluation of Additional Safety Data. The American Journal of Medicine 87 (Suppl. 5A) 37S-39S.
Wise, R., Donovan, I.A., (1987): Tissue penetration and metabolism of Ciprofloxacin. The American Journal of Medicine, 82 (Suppl. 4A) 103–107.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Iqbal, S.M., Murthy, J.G., Banerjee, P.K. et al. Ciprofloxacin ototoxicity. IJO & HNS 48, 168–170 (1996). https://doi.org/10.1007/BF03048074
Issue Date:
DOI: https://doi.org/10.1007/BF03048074