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Closure of persistent central perforations of tympanic membrane using 1% hyaluronic acid

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Abstract

Twenty five dry, small or medium sized persistent central perforations were treated by local application of 1% hyaluronic acid after excision of the perforation rim. The duration of the perforation ranged from two months to forty years. 88 percent perforations healed with 16 ± 4 (S.D.) days using 5 ± 1.6 (S.D.) applications. Hyaluronic acid treatment of dry tympanic membrane perforations not exceeding one quadrant seems to be an alternative to surgical myringoplasty.

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Authors and Affiliations

  1. Department of E.N.T., R.N.T. Medical College, 313 001, Udaipur

    Shiv Kumar & A. K. Gupta

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  1. Shiv Kumar
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  2. A. K. Gupta
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Kumar, S., Gupta, A.K. Closure of persistent central perforations of tympanic membrane using 1% hyaluronic acid. IJO & HNS 47, 127–131 (1995). https://doi.org/10.1007/BF03047943

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  • DOI: https://doi.org/10.1007/BF03047943

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