Abstract
The reactions of benzyl chloride,p-methyl benzyl chloride,p-chloro benzyl chloride, benzyl bromide andp-nitro benzyl bromide with aromatic and heterocyclic bases have been studied in carbon tetrachloride-phenol mixtures. The reactions of amines and pyridine with benzylchloride andp-methyl benzyl chloride have been extended to solvent mixtures like benzene-phenol, nitrobenzene-phenol, nitro-benzene-ethanol and carbontetrachloride-ethanol mixtures and those of amines and pyridine with benzyl bromide andp-nitrobenzyl-bromide have been extended to DMF-phenol mixtures. The results are discussed in the light of basicity, nucleophilicity, electronic, steric and medium effects.
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Communicated by Prof. M. Santappa,f.a.sc., f.n.i.
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Radhakrishnamurti, P.S., Samantara, K.C. Kinetics of reaction of benzyl halides with amines in mixed solvents. Proc. Indian Acad. Sci. 80, 85–92 (1974). https://doi.org/10.1007/BF03046684
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DOI: https://doi.org/10.1007/BF03046684