Abstract
The acetylcholinesterase activity, RNA levels, total free amino acids and magnesium content in fore-, mid- and hind-brain were determined in the normal and hypophysectomised frogs (Rana cyanophlyctus). Hypophysectomy results in a marked decrease in the freea−a and in Mg. RNA also decreases significantly, but not to the same degree as thea−a and Mg. But AchE levels do not change significantly although there is a general decrease. It is suggested that the decrease in Mg is a reflection of the ionic imbalance resulting from hormonal imbalance. Hypophysectomy also results in reduced protein synthesis (and/or turnover) in the CNS as indicated by reduced RNA anda−a.
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Suryaprabha, S., Rao, K.P. Physiological studies on the effects of hormonal imbalance on the central nervous system. Proc. Indian Acad. Sci. 77, 156–165 (1973). https://doi.org/10.1007/BF03045591
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DOI: https://doi.org/10.1007/BF03045591