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Malnutrition bei Hämodialysepatienten

Malnutrition in Hemodialysis Patients: Clinical Assessment versus Patient Self-Assessment

Selbsteinschätzung, ärztliche Beurteilung und „objektivierbare” Parameter

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Zusammenfassung

Hintergrund

Das Auftreten einer Malnutrition bei Dialysepatienten geht mit erhöhter Morbidität und Mortalität einher. Die Therapie einer Mangelernährung bleibt jedoch häufig erfolglos, was durch mangelndes Verständnis des Patienten für die Notwendigkeit einer diätetischen Intervention bedingt sein könnte. Wir untersuchten in dieser Studie, inwieweit die Beurteilung der Ernährung durch Patienten und Arzt übereinstimmt.

Patienten und Methode

Bei 68 chronischen Dialysepatienten wurde der Ernährungsstatus mittels „Subjective Global Assessment” (SGA) erhoben. Im Serum wurden Albumin, Präalbumin, Transferrin und Cholesterin bestimmt, zusätzlich wurde die „Protein-Catabolic-Rate” (nPCR) ermittelt. Mittels Fragebogen wurden die Patienten um eine Beurteilung ihrer Ernährung und ihres Gewichtes gebeten.

Ergebnis

Nach SGA-Kriterien zeigten 34% der Patienten Zeichen der mäßigen bis schweren Malnutrition, bei 45% lag das Serumalbumin < 4,0 g/dl. Albumin korrelierte am besten mit der klinischen Beurteilung, wohingegen Transferrin, Präalbumin, Cholesterin und Protein-Catabolic-Rate schlechtere Korrelationen zeigten. Der Fragebogen wurde von 85% der Patienten beantwortet. In der nach SGA-Kriterien mangelernährten Gruppe beurteilten 84% die eigene Ernährung als „ausreichend”, 79% waren mit dem eigenen Gewicht zufrieden, lediglich 21% beklagten Untergewicht.

Schlußfolgerung

Unsere Untersuchung zeigt, daß bei Hämodialysepatienten häufig eine Fehlbeurteilung der eigenen Ernährungssituation vorliegt. Dies sollte bei der Beratung und Führung mangelernährter Patienten berücksichtigt werden.

Summary

Background

Malnutrition in hemodialysis patients is associated with increased mortality and morbidity. Interventions to treat malnutrition are often ineffective. Underestimation by the patients of the importance of dietary interventions might negatively influence any therapeutic outcome. We examined the correlation between nutritional assessment by the patient himself and clinical assessment by the physician.

Patients and Methods

Subjective global assessment (SGA) was performed in 68 chronic hemodialysis patients. Serum concentrations of albumin, prealbumin, transferrin and cholesterin were measured. Protein intake was estimated by protein catabolic rate (nPCR). In form of a questionaire patients were asked to assess their own nutrition.

Results

According to SGA-criteria, moderate to severe malnutrition was found in 34% of our patients. In this malnourished group serum albumin was <4.0 g/dl in 45% of patients and correlated best with clinical nutritional assessment. Specificity was lower for prealbumin, transferrin, cholesterin, and nPCR. The questionaire was completed by 85% of patients. Self-assessment of their own nutrition was discrepant to clinicla assessment in 84% of malnourished patients. A similar percentage (79%) of malnourished patients considered their own body weight to be adequate, while only 21% indicated desire to gain weight.

Conclusions

Our data indicate that a significant percentage of malnourished hemodialysis patients shows a tendency to overestimate their own nutrition. This may negatively influence patient compliance and should be considered in dietary counseling of malnourished chronic hemodialysis patients.

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Literatur

  1. Baker, J. P., A. S. Detsky, D. E. Wesson, S. L. Wolman, S. Steward, J. Whitewell, B. Langer, K. N. Jeejeebhoy: Nutritional assessment. A comparison of clinical judgment and objective measurements. New Engl. J. Med. 306 (1982), 969–972.

    Article  PubMed  CAS  Google Scholar 

  2. Bergström, J.: Why are dialysis patients malnourished? Amer. J. Kidney Dis. 26 (1995), 229–241.

    Article  Google Scholar 

  3. Bergström, J., B. Lindholm: Nutrition and adequacy of dialysis. How do hemodialysis and CAPD compare? Kidney int. 43, Suppl. 40 (1993), S39-S50.

    Google Scholar 

  4. Blagg, C. R.: Importance of nutrition in dialysis patients. Amer. J. Kidney Dis. 17 (1991), 458–461.

    CAS  Google Scholar 

  5. Cano, N. J., J. P. Fernandez, P. Lacombe, M. Lankester, S. Pascal, M. Defayolle, J. Lebastie, S. Saingra: Statistical selection of nutritional parameters in hemodialysis patients. Kidney int. 32 Suppl. 22 (1987), S178-S180.

    Google Scholar 

  6. Chiappini, M. G., G. Selvaggi, S. Del Signore: Malnutrition as a negativ prognostic index in hemodialyzed patients (abstract). Nephrol. dial. Transplant. 2 (1987), 434.

    Google Scholar 

  7. Ciancaruso, B., G. Brunori, J. D. Kopple, G. Traverso, G. Panarello, G. Enia, P. Strippoli, A. DeVecchi, M. Querques, G. Viglino, E. Vonesh, R. Maiorca: Cross-sectional comparison of malnutrition in continuous ambulatory peritoneal dialysis and hemodialysis patients. Amer. J. Kidney Dis. 26 (1995), 475–486.

    Article  Google Scholar 

  8. Daugirdas, J. F.: The post:pre dialysis plasma urea nitrogen ratio to estimate Kt/V and nPCR: Validation. Int. J. artif. Org. 12 (1989), 420–427.

    CAS  Google Scholar 

  9. Degoulet, P., I. Reach, F. Aime: Risk factors in chronic hemodialysis. Proc. Europ. dial. Transplant. Ass. 17 (1980), 149–154.

    CAS  Google Scholar 

  10. Detsky, A. S., J. R. McLoughlin, J. P. Baker, N. Johnston, S. Whittaker, R. A. Mendelson, K. N. Jeejeebhoy: What is subjective global assessment of nutritional status? J. Parent. Enter. Nutr. 11 (1987), 8–13.

    Article  CAS  Google Scholar 

  11. Enia, G., C. Sicuso, G. Alati, C. Zoccali: Subjective global assessment of nutrition in dialysis patients. Nephrol. dial. Transplant. 8 (1993), 1094–1098.

    PubMed  CAS  Google Scholar 

  12. Fenton, S. S. A., N. Johnston, T. Delmore, A. S. Detsky, J. Whitewell, R. O’Sullivan, D. C. Cattran, R. M. Richardson, K. N. Jeejeebhoy: Nutritional assessment of continuous ambulatory peritoneal dialysis patients. ASAIO Trans. 33 (1987), 650–653.

    PubMed  CAS  Google Scholar 

  13. Gotch, F. A., J. A. Sargent: A mechanistic analysis of the national cooperative dialysis study (NCDS). Kidney int. 28 (1985), 526–534.

    Article  PubMed  CAS  Google Scholar 

  14. Kaysen, G. A., V. Rathore, C. Shearer, T. A. Depner: Mechanisms of hypoalbuminemia in hemodialysis patients. Kidney int. 48 (1995), 510–516.

    Article  PubMed  CAS  Google Scholar 

  15. Kopple, J. D.: Effect of nutrition on morbidity and mortality in maintenance dialysis patients. Amer. J. Kidney Dis. 24 (1994), 1002–1009.

    CAS  Google Scholar 

  16. Kopple, J. D., G. P. Grodstein, C. E. Roberts: Nutritional status of the diabetic patient with chronic uremia. In: Friedman, E. A., F. A. L’Esperance Jr (eds.): Diabetic renal-retinal syndrome. Grune & Straton, Philadelphia 1980, p. 239–252.

    Google Scholar 

  17. Lowrie, E. G., N. L. Lew: Death risk in hemodialysis patients: The predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Amer. J. Kidney Dis. 15 (1990), 458–463.

    CAS  Google Scholar 

  18. Marckmann, P.: Nutritional status of patients on hemodialysis and peritoneal dialysis. Clin. Nephrol. 29 (1988), 75–78.

    PubMed  CAS  Google Scholar 

  19. Morgenstern, A., J. Winkler, R. Narkis: Adequacy of dialysis and nutritional status in hemodialysis patients. Nephron 66 (1994), 438–441.

    Article  PubMed  CAS  Google Scholar 

  20. Owen, W. E. Jr, N. L. Lew, Y. Liu, E. G. Lowrie, J. M. Lazarus: The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. New Engl. J. Med. 329 (1993), 1001–1006.

    Article  PubMed  Google Scholar 

  21. Panzetta, G.: Protein intake does not depend on the dose of dialysis delivered — provided Kt/V is adequate. Nephrol. dial. Transplant. 10 (1995), 2286–2289.

    PubMed  CAS  Google Scholar 

  22. Young, G. A., J. D. Kopple, B. Lindholm, E. F. Vonesh, A. DeVecchi, A. Scalamogna, C. Castelnova, D. G. Oreopoulos, G. H. Anderson, J. Bergström, J. DiChiro, D. Gentile, A. Nissenson, L. Sakhrani, A. M. Brownjohn, K. D. Nolph, B. Prowant, C. E. Algrim, L. Martis, K. D. Serkes: Nutritional assessment of continuous ambulatory peritoneal dialysis patients: An international study. Amer. J. Kidney Dis. 17 (1991), 462–471.

    CAS  Google Scholar 

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Kuhlmann, M.K., Winkelspecht, B., Hammers, A. et al. Malnutrition bei Hämodialysepatienten. Med. Klin. 92, 13–17 (1997). https://doi.org/10.1007/BF03042276

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