Medizinische Klinik

, Volume 94, Supplement 3, pp 84–89 | Cite as

A conservative triple antioxidant approach to the treatment of hepatitis C

Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: Three case histories
  • Burton M. Berkson


Background: There has been an increase in the number of adults seeking liver transplantation for hepatitis C in the last few years and the count is going up rapidly. There is no reliable and effective therapy for chronic hepatitis C since interferon and antivirals work no more than 30% of the time, and liver transplant surgery is uncertain and tentative over the long run. This is because, ultimately, residual hepatitis C viremia infects the new liver. Furthermore, liver transplantation can be painful, disabling and extremely costly.

Treatment Program: The author describes a low cost and efficacious treatment program in 3 patients with cirrhosis, portal hypertension and esophageal varices secondary to chronic hepatitis C infection. This effective and conservative regimen combines 3 potent antioxidants (alpha-lipoic acid [thioctic acid], silymarin, and selenium) that possess antiviral, free radical quenching and immune boosting qualities.

Conclusion: There are no remarkably effective treatments for chronic hepatits C in general use. Interferon and antivirals have less than a 30% response rate and because of the residual viremia, a newly transplanted liver usually becomes infected again. The triple antixoidant combination of alpha-lipoic acid, silymarin and selenium was chosen for a conservative treatment of hepatitis C because these substances protect the liver from free radical damage, increase the levels of other fundamental antioxidants, and interfere with viral proliferation. The 3 patients presented in this paper followed the triple antioxidant program and recovered quickly and their laboratory values remarkably improved. Furthermore, liver transplantation was avoided and the patients are back at work, carrying out their normal activities, and feeling healthy. The author offers a more conservative approach to the treatment of hepatitis C, that is exceedingly less expensive. One year of the triple antioxidant therapy described in this paper costs less than $ 2,000, as compared to mor than $300,000 a year for liver transplant surgery. It appears reasonable, that prior to liver transplant surgery evaluation, or during the transplant evaluation process, the conservative triple antioxidant treatment approach should be considered. If these is a significant betterment in the patient’s condition, liver transplant surgery may be avoided.

Key Words

Hepatitis C Treatment Antioxidant Alpha lipoic acid thioctic acid Silymarin Selenium 

Eine konservative dreifache antioxidante Methode zur Behandlung von Hepatitis C. Eine Kombination von Alpha-Liponsäure (thioctic acid), Silymarin und Selenium: Drei Krankenberichte


Hintergund: Es gibt im Allgemeingebrauch keine bemerkenswert erfolgreiche Behandlung von chronischer Hepatitis C.Interferon und Virostatika haben weniger als eine 30prozentige Ansprechsquote, und wegen der zurückbleibenden Virämia wird meistens eine neu transplantierte Leber wieder infiziert.

Behandlungsprogramm: Die dreifache antioxidante Kombination von Alpha-Liponsäure, Silymarin und Selenium wurde für eine konservative Behandlung von Hepatitis C gewählt, denn diese Stoffe schützen die Leber vor freier radikaler Beschädigung, erhöhten das Niveau anderer fundamentaler Antioxidanzien und hindern virale Fortpflanzung. Die drei Patienten, die in dieser Abhandlung geschildert werden, folgten dem dreifachen antioxidanten Programm, sie erholten sich rasch, und ihre Laborwerte verbesserten sich beachtlich. Außerdem wurden Lebertransplantationen vermieden, die Patienten arbeiten wieder, führen ein normales Leben und fühlen sich gesund.

Schlußfolgerung: Der Autor bieter eine konservativere Methode zur Behandlung von Hepatitis C, die wesentlich billiger ist. Ein Jahr der dreifachen antioxidanten Behandlung, die in dieser Abhandlung beschrieben wird, kostet weniger als $ 2000, eine Lebertransplantation kostet im Vergleich mehr als $ 300.000 im Jahr. Es scheint vernünftig zu sein, bevor eine Lebertransplantationsoperation in Erwägung gezogen wird oder während der Bewertung einer Lebertransplantationsoperation die konservative dreifache Behandlung zu erwägen. Wenn es eine beachtliche Verbesserung im Befinden des Patienten gibt, kann eine Lebertransplantationsoperation vermieden werden.


Hepatitis C Behandlung Antioxidant Alpha-Liponsäure Thiotic acid Silymarin Selenium 


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Copyright information

© Urban & Vogel 1999

Authors and Affiliations

  1. 1.Integrative Medical Centers of New Mexico and Applied Biology (EPPWS Department)Newe Mexico State UniversityLas CrucesUSA

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