Summary
□Basis: Selenium-responsive clinical manifestations of selenium deficiency and elucidation of the biochemical and molecular biological basis of the essentiality of selenium give evidence for the biological importance of the trace element in human nutrition.
□Conclusion: The dietary parenterla selenium requirement can be calculated on the basis of the maximal gene expression of the selenoprotein plasma glutathione peroxidase (plGPx). In total parenteral nutrition a daily requirement of 0.01 µmol/kg body weight for adults and 0.025 µmol/kg body weight for children can be seen as adequate and safe.
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Gramm, H.J., Kopf, A. & Brätter, P. Bedeutung und ernährungsphysiologischer Bedarf des Spurenelementes Selen im Rahmen der parenteralen Ernährung (TPN). Med Klin 92 (Suppl 3), 20–22 (1997). https://doi.org/10.1007/BF03041954
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DOI: https://doi.org/10.1007/BF03041954