Zusammenfassung
Der Anteil von Diabetikern, die in ein Nierenersatzprogramm aufgenommen werden müssen, steigt kontinuierlich und hat in einzelnen Zentren 50% der Patienten erreicht, die neu in die Dialyse aufgenommen werden. Vorbereitung und Planung eines Nierenersatzverfahrens werden dadurch kompliziert, daß der Großteil der Diabetiker dem Nephrologen erst im Stadium des terminalen Nierenversagens vorgestellt wird. Unter den primären Behandlungsoptionen bilden Hämo- und Peritonealdialyse für einen mittelfristigen Zeitraum gleichwertige Therapieverfahren. Bei jüngeren Diabetikern kann eine Nieren- bzw. bei Typ-I-Diabetikern eine kombinierte Nieren-/Pankreastransplantation zu einer besseren Überlebensprognose beitragen. Alle Verfahren ergänzen sich und müssen individuell geplant und im Rahmen eines Langzeitkonzeptes eingesetzt werden. Der primäre Ausschluß älterer und polymorbider Diabetiker von der Dialyse ist in keinem Fall gerechtfertigt.
Summary
The proportion of diabetic patients commencing renal replacement therapy is continuously increasing and in some centers diabetes accounts for 50% of the new patients who enter the dialysis programme. Most of the diabetic patients are referred to the nephrologist at the beginning of end-stage renal failure which means delayed preparation and planning of dialysis therapy. Both, hemodialysis and peritoneal dialysis, offer equal therapeutic options in a medium-term period. Renal and combined renal-pancreatic transplantation in Type I diabetes may contribute to better survival in younger diabetics. All therapeutic options are complementary and have to be applied individually within a long-term treatment concept. The primary exclusion of older and polymorbid diabetic patients from dialysis treatment is not justified.
Literatur
Avram, M. V., P. A. Fein, L. Bonomini, N. Mittman, R. Loutoby, D. K. Avram, J. Chattopadhyay: Predictors of survival in continuous ambulatory dialysis patients: a five-year prospective study. Perit. Dial. Int. 16, Suppl 1 (1996), S190-S194.
Bloembergen, W. E., F. K. Port, E. A. Mauger, R. Wolfe: A comparison of cause of death between patients treated with hemodialysis and peritoneal dialysis. J. Amer. Soc. Nephrol. 6 (1995), 184–191.
Bloembergen, W. E., F. K. Port, E. A. Mauger, R. A. Wolfe: A comparison of mortality between patients treated with hemodialysis and peritoneal dialysis. J. Amer. Soc. Nephrol. 6 (1995), 177–183.
Canada-USA (CANUSA) peritoneal dialysis study group: Adequacy of dialysis and nutrition in continuous peritoneal dialysis: association with clinical outcomes. J. Amer. Soc. Nephrol. 7 (1996), 198–207.
Disney, A. P. S.: Demography and survival of patients receiving treatment for chronic renal failure in Australia and New Zealand: Report on dialysis and renal transplantation treatment from the Australia and New Zealand dialysis and transplant registry. Amer. J. Kidney Dis. 24 (1995), 165–175.
Excerpts from the USRDS annual data report. Amer. J. Kidney Dis. 20, Suppl. 2 (1992), 1–113.
Excerpts from the USRDS 1995 annual data report. Amer. J. Kidney Dis. 26 (1995), S69–S84.
Excerpts from the USRDS 1995 annual data report. ibid., 1995, S95–S111.
Fenton, S., M. Desmeules, P. Coppleston, G. Arbus, D. Froment, L. Jeffery, C. Kjellstrand: Renal replacement therapy in Canada: a report from the Canadian organ replacement register. Amer. J. Kidney Dis. 25 (1995), 134–150.
Friedman, E. A.: Management choices in diabetic endstage renal disease. Nephrol. Dial. Transpl. 10, Suppl. 7 (1995), 61–69.
Geerlings, W., G. Tufveson, J. H. H. Ehrich, E. H. P. Jones, P. Landais, C. Loirat, N. P. Mallick, R. Margreiter, A. E. G. Raine, K. Salmela, N. H. Selwood, F. Valderrabano: Report on management of renal failure in Europe, XXIII. Nephrol. Dial. Transpl. Suppl. 1 (1994), 6–25.
Genestier, S., G. Hedelin, P. Schaffer, B. Faller: Prognostic factors in CAPD patients: a retrospective study of a 10-year period. Nephrol. Dial. Transpl. 10 (1995), 1905–1911.
Lupo, A., R. Tarchini, G. Cancarini, L. Catizone, R. Cocchi, A. De Vecchi, G. Viglino, M. Salomone, G. Segoloni, A. Giangrande: Long-term outcome in continuous ambulatory peritoneal dialysis: a 10-year survey by the Italian cooperative peritoneal dialysis study group. Amer. J. Kidney Dis. 24 (1994), 826–837.
Maiorca, R., G. C. Cancarini, C. Camerini, G. Brunori, L. Manili, E. Movilli, P. Feller, S. Mombelloni: Is CAPD competitive with hemodialysis for long-term treatment of uraemic patients? Nephrol. Dial. Transplant. 4 (1989), 244–253.
Maiorca, R., C. Cancarini, G. Brunori, R. Zubani, C. Camerini, L. Manili, M. Campanini, S. Mombelloni: Which treatment for which patient in the future? Possible modifications in CAPD. Nephrol. Dial. Transpl. 10, Suppl. 7 (1995), 20–26.
Maiorca, R., G. C. Cancarini, R. Zubani, C. Camerini, L. Manili, G. Brunori, E. Movilli: CAPD viability: a long-term comparison with hemodialysis. Perit. Dial. Int. 16 (1996), 276–287.
Marcelli, D., D. Spotti, F. Conte, A. Tagliaferro, A. Limido, F. Lonati, F. Malberti, F. Locatelli: Survival of diabetic patients on peritoneal dialysis or hemodialysis. Perit. Dial. Transpl. 16, Suppl. 1 (1996), 283–287.
Prichard, S. S.: Treatment modality selection in 150 consecutive patients starting ESRD therapy. Perit. Dial. Int. 16 (1996), 69–72.
Raine, A. E. G.: Evolution worldwide of the treatment of patients with advanced diabetic nephropathy by renal replacement therapy. In: Morgenson, C. E. (ed.): The kidney and hypertension in diabetes mellitus. Kluwer Academic Publishers, Boston Dordrecht London, 2nd edition, 1996, 449–458.
Sollinger, H. W., R. J. Poeg, D. E. Eckhoff, M. D. Stegall, R. Isaacs, J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, M. Kalyuglu, F. O. Blezer: Two hundred consecutive simultaneous pancreas-kidney transplants with bladder drainage. Surgery 114 (1993), 736–743.
Teehan, B. P., C. R. Schleifer, J. Brown: Adequacy of continuous ambulatory peritoneal dialysis: morbidity and mortality in chronic peritoneal dialysis. Amer. J. Kidney Dis. 24 (1994), 990–1001.
Thomae, U., R. Kuhnt, H. Exner: Hämodialyse oder kontinuierliche ambulante Peritonealdialyse (CAPD) bei niereninsuffizienten Diabetikern. Nieren-u. Hochdruckkrankheiten 23 (1994), 25–30.
Valderrabano, F., E. H. P. Jones, N. P. Mallick: Report on management of renal failure in Europe, XXIV, 1993. Nephrol. Dial. Transpl. 10, Suppl. 5 (1995), 1–25.
Valderrabano, F., F. C. Berthoux, E. H. P. Jones, O. Mehls: Report on management of renal failure in Europe, XXV, 1994. End stage renal disease and dialysis report. Nephrol. Dial. Transpl. 11, Suppl. 1, 2–21.
Viberti, G. C., C. E. Mogenson, P. Passa, R. Bilous, R. Mangili: St Vincent Declaration, 1994: Guidelines for the prevention of diabetic renal failure. In: Mogenson, C. E., ibid., 1994, S. 515–527.
Zimmerman, S. W., L. L. Oxton, D. Bidwell, M. Wakeen: Long-term outcome of diabetic patients receiving peritoneal dialysis. Perit. Dial. Int. 16 (1996), 63–68.
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Pommer, W. Primäre Optionen der Nierenersatztherapie für Diabetiker. Med. Klin. 92 (Suppl 1), 35–39 (1997). https://doi.org/10.1007/BF03041808
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DOI: https://doi.org/10.1007/BF03041808