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The cost-effectiveness of mixed beam neutron-photon radiation therapy in the treatment of adenocarcinoma of the prostate

  • Epidemiology and Socio-Economical Aspects
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Summary

The results of clinical trials in the treatment of adenocarcinoma of the prostate using, mixed beam neutron/photon therapy, neutrons alone and photon therapy in combination with hormone treatment are compared. These trials indicate that neutron therapy is superior to photon/hormone therapy in achieving local control. The costs of delivering these two different therapies in a large US academic radiation oncology center at Wayne State University (WSU) are compared. The cost of a full course of mixed beam therapy is $20,142 compared to $18,871 for the photon/hormone treatment. Although the WSU neutron facility is a state-of-the-art installation, it is also a prototype device; it is estimated that a modern neutron facility based on this design would operate more cost effectively reducing the cost of a course of mixed beam therapy to $ 18,532.

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References

  1. Forman JD. Tekyl-Mensah S, Caudrelier J-M, et al. Neutron irradiation in the management of localized and locally advanced prostate cancer. In Amico AD, Hanks GE (Eds.): Advances in Radio-therapeutic Management of Carcinoma of the Prostate. Lippincott Williams and Wilkins, New York, in press.

  2. Laramore GE, Krall JM, Thomas FJ, et al. Fast neutron radiotherapy for locally advanced prostate cancer: final report of an RTOG randomized clinical trial. Am J Clin Oncol 1993;16:164–7.

    Article  PubMed  CAS  Google Scholar 

  3. Maughan RL, Powers WE, Blosser HG. A super-conducting cyclotron for neutron radiation therapy. Med Phys 1994;21:779–85.

    Article  PubMed  CAS  Google Scholar 

  4. Pilepich MV, Sause WT, Shipley WU, et al. Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: a randomized comparative trial of the Radiation Therapy Oncology Group. Urology 1995;45:616–23.

    Article  PubMed  CAS  Google Scholar 

  5. Russell KJ, Caplan R, Laramore GE, et al. Photon versus fast neutron external beam radiotherapy in the treatment of locally advanced prostate cancer: results of a randomized prospective trial. Int J Radiat Oncol Biol Phys 1994;28:47–54.

    PubMed  CAS  Google Scholar 

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Correspondence to Richard L. Maughan.

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Maughan, R.L., Brambs, B., Porter, A.T. et al. The cost-effectiveness of mixed beam neutron-photon radiation therapy in the treatment of adenocarcinoma of the prostate. Strahlenther Onkol 175 (Suppl 2), 104–107 (1999). https://doi.org/10.1007/BF03038905

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  • DOI: https://doi.org/10.1007/BF03038905

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