Skip to main content
Log in

Nuclear data for radiotherapy: Presentation of a new ICRU report and IAEA initiatives

  • Accelerator and Medical Physics
  • Published:
Strahlentherapie und Onkologie Aims and scope Submit manuscript

Summary

An ICRU report entitled “Nuclear Data for Neutron and Proton Radiotherapy and for Radiation Protection” is in preparation. The present paper presents an overview of this report, along with examples of some of the results obtained for evaluated nuclear cross sections and kerma coefficients. These cross sections are evaluated using a combination of measured data and the GNASH nuclear model code for elements of importance for biological, dosimetric, beam modification and shielding purposes. In the case of hydrogen both R-matrix and phase-shift scattering theories are used. In the report neutron cross sections and kerma coefficients will be presented up to 150 MeV and proton cross sections up to 250 MeV.

An IAEA Consultants’ Meeting was also convened to examine the “Status of Nuclear Data needed for Radiation Therapy and Existing Data Development Activities in Member States”. Recommendations were made regarding future endeavours.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Awschalom M, Rosenberg I, Mravca A. Kerma for various substances averaged over the spectra of fast neutron therapy beams: a study in uncertainties. Med Phys 1983;10:395–409.

    Article  PubMed  CAS  Google Scholar 

  2. Benck, S, Slypen I, Meulders J-P, et al. Light charged particle production induced by fast neutrons on carbon, oxygen and aluminium. In: Reffo G, Ed. Proc of the International Conference on Nuclear Data for Science and Technology, Trieste, Italy, 1997. Bologna, Italy: ENEA (in press).

  3. Bertrand FE, Peelle RW. Complete hydrogen and helium particle spectra from 30 to 60 MeV proton bombardment on nuclei with A=12 to 209 and comparison with the intranuclear cascade model. Phys Rev 1973;8:1045–64.

    Article  CAS  Google Scholar 

  4. Binns PJ. Personal Communication, 1998.

  5. Brenner DJ, Prael RE. Calculated differential secondary-particle production cross sections after nonelastic neutron interactions with carbon and oxygen between 15 and 60 MeV. Atomic Data and Nuclear Data Tables 1989;41:71–130.

    Article  CAS  Google Scholar 

  6. Caswell RS, Coyne JJ, Randolph ML. Kerma factors for neutron energies below 30 MeV. Rad Res 1980;83:217–54.

    Article  CAS  Google Scholar 

  7. Chadwick MB, Blann M, Cox LJ, et al. Calculation and evaluation of cross sections and kerma factors for neutrons up to 100 MeV on carbon. Nucl Sci Eng 1996;123:17–37.

    CAS  Google Scholar 

  8. Chadwick MB, Young PG. Calculation and evaluation of cross sections and kerma factors for neutrons up to 100 MeV on16O and14N. Nucl Sci Eng 1996;123:1–16.

    CAS  Google Scholar 

  9. Chadwick MB, Young PG, MacFarlane RE, et al. Cross section evaluations to 150 MeV for accelerator-driven systems and implementation in MCNPX. Nucl Sci Eng (submitted 1998).

  10. Cowley AA. Personal Communication, 1997.

  11. Dimbylow PJ. Neutron cross-section and kerma value calculations for C, N, O, Mg, Al, P. S, Ar and Ca from 20 to 50 MeV. Phys Med Biol 1982;27:989–1001.

    Article  CAS  Google Scholar 

  12. Förtsch SV, Cowley AA, Pilcher JV, et al. Continuum yields from12C(p-p) at incident proton energies of 90 and 200 MeV. Nucl Phys 1988;A485:258–70.

    Article  Google Scholar 

  13. Haight RC, Lee TM, Sterbenz SM, et al. Alpha-particle emission from carbon bombarded with neutrons below 30 MeV. In: Dickens JK, Ed. Proc of the International Conference on Nuclear Data for Science and Technology, Gatlinburg, TN. La Grange Park IL: American Nuclear Society 1994:311–3

    Google Scholar 

  14. ICRU Report 45. Clinical neutron dosimetry. Part 1: Determination of absorbed dose in a patient treated by external beams of fast neutrons. Bethesda, MD: International Commission on Radiation Units and Measurements, 1989.

  15. ICRU Report 59. Clinical proton dosimetry. Part 1: Beam production, beam delivery and measurement of absorbed dose. Bethesda MD: International Commission on Radiation Units and Measurements, 1997.

  16. McDonald JC, Cummings FM. Calorimetric measurements of carbon and A-150 plastic kerma factors for 14.6 MeV neutrons. Rad Prot Dosim 1988;23:31–3.

    CAS  Google Scholar 

  17. Meier MM, Clark DA, Goulding CA, et al. Differential neutron production cross sections and neutron yields from stopping-length targets for 113-MeV protons. Nucl Sci Eng 1989;102:310–21.

    CAS  Google Scholar 

  18. Meier MM, Amian WB, Goulding CA, et al. Differential neutron-production cross-sections for 256 MeV protons. Nucl Sci Eng 1992;110:289–98.

    CAS  Google Scholar 

  19. Menzel H, Bhler G, Schuhmacher H, et al. Ionization distributions and A-150 plastic kerma for neutrons between 13.9 and 19.0 MeV measured with a low pressure proportional counter. Phys Med Biol 1984;29:1537–54.

    Article  CAS  Google Scholar 

  20. Mijnheer BJ, Wootton P, Williams JR, et al. Uniformity in dosimetry protocols for therapeutic applications of fast neutron beams. Med Phys 1987;14:1020–6.

    Article  PubMed  CAS  Google Scholar 

  21. Nauchi Y, Baba M, Sanami T, et al. Measurement of (n,xp) and (n,xd) double differential cross sections of Al and C for ten’s MeV neutrons. In: Reffo G, Ed. Proc of the International Conference on Nuclear Data for Science and Technology, Trieste, Italy, 1997. Bologna, Italy: ENEA (in press).

  22. Pihet P, Guldbakke S, Menzel HG, et al. Measurement of kerma factors for carbon and A-150 plastic: neutron energies from 13.9 to 20.0 MeV. Phys Med Biol 1992;37:1957–76.

    Article  Google Scholar 

  23. Schrewe UJ, Brede HJ, Gerdung S, et al. Determination of kerma factors of A-150 plastic and carbon at neutron energies between 45 and 66 MeV. Rad Prot Dosim 1992;44:21–4.

    CAS  Google Scholar 

  24. Schrewe UJ, Newhauser WD, Brede HJ, et al. Neutron kerma factor measurements in the energy range between 5 MeV and 66 MeV. In: Reffo G, Ed. Proc of the International Conference on Nuclear Data for Science and Technology, Trieste, Italy, 1997. Bologna, Italy: ENEA (in press).

  25. Schuhmacher H, Brede HJ, Henneck R, et al. Measurement of neutron kerma factors for carbon and A-150 plastic at neutron energies of 26.3 MeV and 37.8 MeV. Phys Med Biol 1992;37:1265–81.

    Article  Google Scholar 

  26. Slypen I, Corcalciuc V, Meulders J-P. Proton and deuteron production in neutron-induced reactions on carbon at En=42.5, 62.7 and 72.8 MeV. Phys Rev 1995;C51:1303–11.

    Article  CAS  Google Scholar 

  27. Slypen I, Corcalciuc V, Meulders J-P, et al. Triton and alpha-particle production in neutron-induced reactions on carbon at En=42.5 MeV, 62.7 MeV and 72.8 MeV. Phys Rev 1996;C53:1309–18.

    Article  CAS  Google Scholar 

  28. Subramanian JL, Romero JL, Brady FP, et al. Double differential inclusive hydrogen and helium spectra from neutron-induced reactions on carbon at 27.4, 39.7 and 60.7 MeV. Phys Rev 1983;C28:521–8.

    Article  CAS  Google Scholar 

  29. Subramanian TS, Romero JL, Brady, FP, et al. Double differential inclusive hydrogen and helium spectra from neutron-induced reactions at 27.4, 39.7 and 60.7 MeV: oxygen and nitrogen. Phys Rev 1986;C34:1580–7.

    Article  CAS  Google Scholar 

  30. Wuu C, Milavickas L. Determination of the kerma factors in tissue-equivalent plastic, C, Mg and Fe for 14.7. MeV neutrons. Med Phys 1987;14:1007–14.

    Article  PubMed  CAS  Google Scholar 

  31. Young PG, Arthur ED, Chadwick MB. Comprehensive nuclear model calculations: introduction to the theory and use of the GNASH code. Technical Report LA-12343-MS. Los Alamos NM: Los Alamos National Laboratory, 1992.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mark B. Chadwick PhD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chadwick, M.B., Jones, D.T.L., Barschall, H.H. et al. Nuclear data for radiotherapy: Presentation of a new ICRU report and IAEA initiatives. Strahlenther Onkol 175 (Suppl 2), 26–29 (1999). https://doi.org/10.1007/BF03038882

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03038882

Key Words

Navigation