Abstract
The michael adducts2a,b were obtained from the reaction of the phenylacetyl derivative1 with benzaldehyde and p-anisaldehyde respectively.2a and2b were subjected to react with cyanoethanoic acid hydrazide, malononitrile, cyanothioacetamide, cyanoacetamide and 1,1,3-tricyano-2-amino propene to yield4a-h and5a,b respectively. Hydrogen peroxide oxidation of2a,b gave the aurone derivative6a,b. The pyrone derivatives8a,b were obtained from2a,b by addition of chloroacetyl chloride followed by dehydrochlorination.
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Hishmat, O.H., El-Diwani, H.I., Bakr, S.M.A. et al. Synthesis and pharmacological studies of some pyrone and benzodifuran derivatives. Arch. Pharm. Res. 16, 168–174 (1993). https://doi.org/10.1007/BF03036869
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DOI: https://doi.org/10.1007/BF03036869