Abstract
Objective: Due to the paucity of reports evaluating stress induced by thoracoscopic surgery with minithoracotomy, we assessed this stress based on the inflammatory response to surgery.Methods: Differences in pre- and postoperative peripheral white blood cell (WBC) count, serum C-reactive protein (CRP), and serum interleukin-6 (IL-6) were evaluated, defined as dW, dCRP, and dIL-6. Thoracoscopic partial lung resection cases were divided into 2 groups by access route: Group A patients in which surgery was concluded via several small access ports. and Group B patients going surgery via small access ports plus minithoracotomy. We also compared dW in standard lobectomy with exploratory thoracotomy (thoracotomy without lobectomy) cases.Results: No significant difference was seen in dW, dCRP, or dIL-6 between groups. dW in response to exploratory thoracotomy was lower than that in standard lobectomy (p=0.06).Conclusions: Surgical stress induced by thoracoscopic partial lung resection does not increase significantly when minithoracotomy is added. Postoperative inflammatory response may, however, be influenced by the extent of surgical trauma.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Naruke T. Thoracoscopic surgery for lung tumor. J Jap Med Assoc 1996; 116: 1785–9.
Mae M, Onuki T, Nishiuchi M, Seto T, Gomi H, Sasano S, et al. Change of CK and CRP values after thoracoscopic surgery for spontaneous pneumothorax (Eng abstr). J Jap Assoc for Chest Surg 1993; 7: 41–5.
Watanabe S, Tsunezuka Y, Sato H. Video-assisted thoracoscopic surgery (VATS) versus thoracotomy for spontaneous pneumothorax (Eng abstr). J Jap Assoc for Chest Surg 1998; 12: 26–31.
Hirata S, Yatuyanagi E, Yamazaki K, Sugimoto Y, Moriyama H, Koshiko T, et al. Changes and modulation of interleukin-6 of perioperative periods with chest surgery (Eng abstr). J Jap Assoc for Chest Surg 1998; 12: 54–58.
Moore FD: Metabolic care of the surgical patient. Philadelphia; W. B. Saunders, 1959
Ueo H, Honda M, Adachi M, Inoue H, Nakashima H, Ainaga S, et al. Minimal increase in serum interleukin-6 levels during laparoscopic cholecystectomy. Am J Surg 1994; 168: 358–60.
Sakamoto K, Arakawa H, Minota S, Ishikawa T, Sugita H, Samejima H, et al. Factors influencing the increase of serum IL-6 concentration in surgical patients (Eng abstr). Nihon Shokaki Gekagakkai Zasshi 1992; 25: 2590–4.
Ueo H, Inoue H, Honda M, Uchida I, Nishimura M, Ainaga S, et al. Production of interleukin-6 at operative wound sites in surgical patients. J Am Coll Surg 1994; 179: 326–32.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kuda, T., Kamada, Y., Nagamine, N. et al. Evaluation of inflammatory-response-induced thoracoscopic surgical stress. Jpn J Thorac Caridovasc Surg 50, 206–209 (2002). https://doi.org/10.1007/BF03032287
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF03032287