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Diaphyseal medullary stenosis with pleomorphic malignant fibrous histiocytoma of the bone:99mTc hydroxymethylenediphosphonate and201Tl chloride scintigraphy findings

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Abstract

Diaphyseal medullary stenosis (DMS) is an extremely rare hereditary bone dysplasia, which was first described by Arnold in 1973. DMS has a high incidence of pleomorphic malignant fibrous histiocytoma (MFH). In this paper, we report the imaging findings of DMS with pleomorphic MFH of the bone, mainly describing99mTc hydroxymethylenediphosphonate (HMDP) and thallium-201 (2OIT1) chloride scintigraphy findings. On99mTc HMDP scintigraphy, focal increased uptake area of the right femur corresponded to the area of bone marrow invasion of the tumor and bone infarction. The mechanism of the uptake of99mTc HMDP to the extraosseous lesion was not clear. On201Tl chloride scintigraphy, the increased uptake of the periphery of the mass seemed to reflect the aggressiveness of invasion and the cellularity.

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Authors and Affiliations

  1. Division of Diagnostic Radiology and Nuclear Medicinea, National Cancer Center Hospital and Research Institute, 5-1-1, Tsukiji, Chuo-ku, 104-0045, Tokyo, Japan

    Mototaka Miyake, Ukihide Tateishi, Tetsuo Maeda & Yasuaki Arai

  2. Pathology Division, National Cancer Center Hospital and Research Institute, Japan

    Tadashi Hasegawa

  3. Division of Radiology, Kobe University Graduate School of Medicine, Japan

    Kazuro Sugimura

Authors
  1. Mototaka Miyake
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  2. Ukihide Tateishi
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  3. Tetsuo Maeda
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  4. Yasuaki Arai
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  5. Tadashi Hasegawa
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  6. Kazuro Sugimura
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Miyake, M., Tateishi, U., Maeda, T. et al. Diaphyseal medullary stenosis with pleomorphic malignant fibrous histiocytoma of the bone:99mTc hydroxymethylenediphosphonate and201Tl chloride scintigraphy findings. Ann Nucl Med 20, 233–236 (2006). https://doi.org/10.1007/BF03027436

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  • DOI: https://doi.org/10.1007/BF03027436

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