Summary
This paper is the first part of a report on a method of measuring FRC by the helium dilution method in anaesthetized children during artificial ventilation. It describes laboratory investigations of the effects of different concentrations of oxygen, nitrogen and methoxyflurane upon the accuracy with which known volumes can be determined in a “dummy lung.” For a volume of 500 ml the coefficient of variation was <4.7; for 1500 ml it was <1.25. Results of using the technique to measure changes in FRC in anaesthetized paralysed children are to be reported in Part II.
Résumé
Cet article est la première partie d'un rapport sur la méthode de mesurer la C.R.F. par la dilution d'hélium chez les enfants anesthésiés et ventilés artificiellement. Nous décrivons les recherches de laboratoire sur les effets de différentes concentrations d'oxygène, d'azote et de méthoxyflurane sur la précision avec laquelle des volumes connus peuvent être déterminés dans un poumon robot. Pour un volume de 500 ml le coefficient de variation était <4.7; pour 1500 ml, il était <1.25. Les résultats de l'usage de la technique pour mesurer les changements de la C.R.F. chez des enfants anesthésiés et paralysés paraîtront dans la deuxième partie.
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This work was supported by a grant from The Physicians' Services Incorporated Foundation and grant number MA-3761 from The Medical Research Council of Canada. Some of the apparatus used in this investigation was purchased with the aid of a grant from the Canadian Red Cross Youth (Ontario).
Paper read by T.L. Dobbinson at the Royal Australasian College of Surgeons 45th General Scientific Meeting, Hobart, Tasmania, 1972.
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Dobbinson, T.L., Nisbet, H.I.A., Pelton, D.A. et al. Functional residual capacity (FRC) and compliance in anaesthetized paralysed children. Canad. Anaesth. Soc. J. 20, 310–321 (1973). https://doi.org/10.1007/BF03027169
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DOI: https://doi.org/10.1007/BF03027169