Summary
Ventilatory responses of dogs to hypercarbia were measured during normothermia and at two levels of hypothermia. A technique of continuous spirometry was used to determine the minute ventilation. Minute ventilation and resting control PaCO 2 fell with decreasing body temperatures. In addition, a progressive decrease was observed in ventilatory responsiveness to inhalation of increased carbon dioxide. In this study the resting ventilation maintained the PaCO 2 lower during hypothermia even though ventilatory responsiveness to carbon dioxide challenge was markedly depressed.
Résumé
Nous avons mesuré, durand la normothermie et sous deux différents niveaux d'hypothermie, les réponses ventilatoires à l'hypercarbie chez des chiens. Nous avons employé une technique de spirométrie continuelle pour déterminer la ventilation minute. A mesure que s'baissait la température corporelle, s'abaissaient également la ventilation minute et le contrôle de la PaCO 2 de repos. De plus, nous avons observé une diminution progressive de la réponse ventilatoire à l'inhalation d'un taux accru de dioxyde de carbone. Durant cette étude, la ventilation de repos a maintenu la PaCO 2 plus basse durant l'hypothermie même si la réponse ventilatoire au dioxyde de carbone était fortement déprimée.
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From the Department of Anaesthesia, University of Toronto.
An erratum to this article is available at http://dx.doi.org/10.1007/BF03006916.
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Sodipo, J.O., Lee, D.C. Comparison of ventilation responses to hypercapnia at normothermia and hypothermia during halothane anaesthesia. Canad. Anaesth. Soc. J. 18, 426–433 (1971). https://doi.org/10.1007/BF03025694
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DOI: https://doi.org/10.1007/BF03025694