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The unreasonable effectiveness of mathematics in molecular biology

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References

  1. Wigner, E.P. (1960). The unreasonable effectiveness of mathematics in the natural sciences.Communications in Pure and Applied Mathematics 13, 1–14.

    Article  MATH  Google Scholar 

  2. Sankoff, D. and Kruskal, J.B., eds. (1983).Time Warps, String Edits, and Macromolecules: The Theory and Practice of Sequence Comparison. Addison-Wesley, Reading, Mass.

    Google Scholar 

  3. Needleman, S.B. and Wunsch, C.D. (1970). A general method applicable to the search for similarities in the amino acid sequence of two proteins.J. Mol. Biol. 48, 443–453.

    Article  Google Scholar 

  4. Fitch, W.M. and Smith, T.F. (1983). Optimal sequence alignments.Proc. Natl. Acad. Sci. USA 80, 1382–1386.

    Article  Google Scholar 

  5. Golub, G. and van Loan, C.,Matrix Computations. Johns Hopkins Press. Baltimore, 2nd ed. 1989.

    MATH  Google Scholar 

  6. Young, G. and Householder, A.S. (1938). Discussion of a set of points in terms of their mutual distances.Psychometrika 3, 19–22. (For background and history see [7].)

    Article  MATH  Google Scholar 

  7. Blumenthal, L.M. (1938).Distance Geometries. A study of the development of abstract metrics. University of Missouri Studies 13, #2.

  8. New York Times, March 25, 1997.

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Authors and Affiliations

  1. Department of Haematology Cambridge Institute for Medical Research, University of Cambridge, CB2 2QH, Cambridge, UK

    Arthur M. Lesk

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  1. Arthur M. Lesk
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Correspondence to Arthur M. Lesk.

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Based on a talk delivered at the final symposium of the program, “Biomolecular Function and Evolution in the Context of the Genome Project,” at The Isaac Newton Institute for the Mathematical Sciences, Cambridge, U.K., 20 Dec. 1998.

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Lesk, A.M. The unreasonable effectiveness of mathematics in molecular biology. The Mathematical Intelligencer 22, 28–37 (2000). https://doi.org/10.1007/BF03025372

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