Conclusion
L’EE est actuellement l’examen le plus précis pour le diagnostic de petites lésions pancréatiques (<25 mm), le développement de la ponction guidée a permis d’augmenter la spécificité de l’EE. Néanmoins, l’EE reste très opérateur dépendante et son résultat doit toujours être intégré dans une prise en charge thérapeutique multidisciplinaire, surtout depuis l’apparition de nouvelles armes thérapeutiques comme la radio-chimiothérapie préopératoire [30], l’utilisation de nouvelles drogues chimiques comme la Gemcitabine [31] et la thérapie cellulaire guidée par échoendoscopie [32].
Conclusion
Endoscopic ultrasonography is the most precise exploration for the diagnosis of small pancreatic lesions measuring less than 25 mm. The development of EUS-guided biopsy has further improved the diagnostic specificity. Nevertheless, EUS remains highly operator-dependent and the result must always be integrated into a multidisciplinary approach to therapeutic management, particularly since the advent of new therapeutic methods such as preoperative radiochemotherapy [30] and the use of new drugs such as gemcitabine [31] and EUS-guided cell therapy [32].
Références
TIO T.L., TYTGAT G.N.J., CIKOT R.J.L.M.et al. — Ampullopancreatic carcinoma: preoperative TNM classification with endosonography.Radiology, 1990,175, 455–461.
KALLIMANIS G., ANXIOTIS E., PAPANTONIOU P.et al. — Endoscopic ultrasonography in preoperative TNM classification of pancreatic cancer.Endoscopy, 1992,24, 656 (abstract)
PALAZZO L., ROSEAU G., GAYET B.et al. — Endoscopic ultrasonography in the diagnosis and the staging of pancreatic adenocarcinoma. Results of a prospective study with comparison to ultrasonography and CT scan.Endoscopy, 1993,25, 143–150.
WIERSEMA M., CHAK A., HAWES R.H.et al. — Evaluation of endosonography in distinguishing malignant from inflammatory pancreatic masses.Gastrointest. Endosc., 1993,39, A336 (abstract).
YASUDA K., MUKAI H., NAKAJIMA M.et al. — Staging of pancreatic carcinoma by endoscopic ultrasonography.Endoscopy, 1993,25, 151–155.
GIOVANNINI M., SEITZ J.F. — Endoscopic ultrasonography with a linear type echoendoscope in the evaluation of 94 patients with pancreatobiliary disease.Endoscopy, 1994,26, 579–585.
MÜLLER M.F., MEYENBERGER C., BERTSCHINGER P.et al. — Pancreatic tumors: Evaluation with endoscopic US, CT and MR imaging.Radiology, 1994,190, 745–751.
BUSCAIL L., PAGES P., BARTHELEMY P., FOURTANIER G., FREXINOS J., ESCOURROU J. — Role of EUS in the management of pancreatic and ampullary carcinoma: a prospective study assessing resectability and prognosis.Gastrointest. Endosc., 1999,50, 34–40.
RÖSCH T. — Staging of pancreatic cancer. Analysis of literature. Results.Gastrointest. Endosc. Clinics of North America. 1995,4, 735–739.
MIDWINTER M.J., BEVERIDGE C.J., WILSDON J.B., BENETT M.K., BAUDOIN C.J., CHARNLEY R.M. — Correlation between spiral computed tomography, endoscopic ultrasonography and findings at operation in pancreatic and ampullary tumors.Brit. J. Surg., 1999,86, 189–193.
BENDER G.N., CASE B., TSUCHIDA A., TIMMONS J.H., WILLIARD W., LYONS M.F., MAKUCH R.V. — Using sector endoluminal ultrasound to identify the normal pancreas when axial computed tomography is falsely positive.Invest. Radiol., 1999,34, 71–74.
MERTZ H., SECHOPOULOS P., DELBEKE D., STEVEN D., LEACH D. — EUS, PET, and CT scanning for evaluation of pancreatic adenocarcinoma.Gastrointest. Endosc., 2000,52, 367–370.
RÖSCH T., DITTLER H.J., STROBEL K.et al. — Local staging of pancreatic head cancer by endoscopic ultrasonography: A reevaluation using blind video-tape assessment.Endoscopy, 1995,27, 768 (abstract)
RÖSCH T., BRAIG C., CAIN T.et al. — Staging of pancreatic and ampullary carcinoma by endoscopic ultrasonography.Gastroenterology, 1992,102, 188–199.
GIOVANNINI M. — Endoscopic ultrasonography with a curved array transducer: normal echoanatomy of the retroperitoneum.Gastrointest Endosc. Clinics of North America, July 1995,5, 523–528.
LEGMANN P., VIGNAUX O., DOUSSET, B., BARAZZA A.J., PALAZZO L., DUMONTIERet al. — Pancreatic tumors: comparison of dual phase helical CT and Endoscopic sonography.Am. J. Roentgenol., 1998,170, 1315–1322.
VILMANN P., HANCKE S., HENRICSKEN F.W., JACOBSEN G.K. — Endoscopic ultrasonography with fine needle aspiration biopsy in pancreatic disease.Endoscopy, 1993,25, 523–527.
GIOVANNINI M., SEITZ J.F., MONGES G., PERRIER H., RABBIA I. — Fine needle aspiration cytology guided by endoscopic ultrasonography: results in 141 patients.Endoscopy, 1995,27, 171–177.
PALAZZO L., FABRE M., AMARIS J., O'TOOLE D., RUSZNIEWSKI Ph. — EUS guided fine needle aspiration biopsy with a new electronic device: results on 100 consecutive patients.Endoscopy, 2000,32, A10 (P21).
WIERSEMA M., VILMANN P., GIOVANNINI M., CHANG K.J. — Endosonography-guided fine needle aspiration biopsy: diagnostic accuracy and complication assessment.Gastroenterology, 1997,112, 1087–1095.
CHANG K.J., WIERSEMA M., GIOVANNINI M., VILMANN P., ERICKSON R.A. — Multi-center collaborative study on endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) of the pancreas.Gastrointestinal Endoscopy, 1996,43 (abstract), 507, 417.
GIOVANNINI M., MONGES G., BERNARDINI B., MOUTARDIER V., SEITZ J.F., HOUVENAEGHEL G., DELPERO J.R. — Therapeutic impact of EUS guided biopsy of solid pancreatic masses. Results in 234 patients.Endoscopy, 1999, suppl. UEGW 99.
BHUTANI M. — Endoscopic ultrasonography in pancreatic disease.Sem. Gastrointest. Dis., 1998,9 (2), 51–60.
WILLIAMS D.B., SAHAI A.V., AABAKEN L., PENMANN I.D., VAN VELSE A., WEBB J., WILSON M.et al. — Endoscopic ultrasound guided fine needle aspiration biopsy: a large single centre experience.Gut, 1999,44 (5), 720–726.
WIERSEMA M.J. — Endosonography guided celiac plexus neurolysis. In Interventional Endoscopic Ultrasonography. 1999, Harwood Academic publishers. M. Bhutani, Chapter 15, 117–123.
GRESS F., GIACCA D., KIEL J., SHERMAN S., LEHMAN G. — Endoscopic ultrasound guide celiac plexus block for management of pain due to chronic pancreatitis.Gastrointest. Endosc., 1997,45, 594 (abstract).
CALENDER A. — New insights in genetics of digestive neuroendocrine tumors. Recent advances in the Physiopathology an Management of inflammatory Bowel diseases and digestive endocrine tumors. M. Mignon, J.F. Colombel, eds, John Libbey Eurotext, Paris, 1999, 155–176.
JENSEN N.T. — Natural history of digestive endocrine tumors. Recent advances in the Physiopathology an Management of inflammatory Bowel diseases and digestive endocrine tumors. M. Mignon, J.F. Colombel, eds, John Libbey Eurotext, Paris, 1999, 192–219.
MOERTEL C.G., KVOLS L.Kv, O'CONNEL M.J.et al. — Treatment of neuroendocrine carcinomas with combined etoposide and cisplatin.Cancer, 1991, 68, 227–232.
SNADY H., BRUCKNER H., COOPERMAN A., PARADISO J., KIEFER L. — Survival advantage of combined chemoradiotherapy compared with resection as the initial treatment of patients with regional pancreatic carcinoma.Cancer, 2000,89, no 2, 314–327.
BURRIS H., MOORE M., ANDERSEN J., GREEN M.R., ROTHENBERG M.L., CRIPPS M.C.et al. — Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreatic cancer: a randomized trial.J. Clin. Oncol., 1997,15, 2403–2413.
CHANG R.J., NGUYEN P.T., THOMPSON J.A.et al. — Phase I clinical trial of local immunotherapy (cytoimplant) delivered by endoscopic ultrasound (EUS)-guided fine needle injection (FNI) in patients with advanced pancreatic carcinoma.Gastrointest. Endosc., 199847, 144 (abstract).
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Giovannini, M. Qu’apporte l’échoendoscopie dans le cancer du pancréas?. Acta Endosc 31, 43–55 (2001). https://doi.org/10.1007/BF03023651
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DOI: https://doi.org/10.1007/BF03023651
Mots-clés
- adénocarcinome du pancréas
- biopsies guidées sous échoendoscopie
- échoendoscopie
- tumeur neuroendocrine du pancréas