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Pertes et profits de l’analgésie péridurale

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Douleur et Analgésie

Résumé

L’antalgie post-opératoire est actuellement un sujet largement débattu. Bien que des progrès incontestables aient été réalisés dans le domaine de la physiologie et de la pharmacologie de la douleur, ainsi que dans la technologie médicale, il ressort des études récentes qu’un nombre encore élevé de patients souffrent de manière inacceptable après une opération. L’analgésie péridurale est une forme d’antalgie bien reconnue, mais également souvent débattue. Aussi, aborder ce sujet sous la forme d’une analyse coût/bénéfice pour le patient paraît pertinent. Les avantages de l’analgésie péridurale sont bien connus et indépendamment de la qualité même de l’analgésie il faut également y trouver des «profits secondaires», tels l’impact favorable sur la fonction pulmonaire, sur la maladie thromboembolique, sur la réponse au stress chirurgical, sur la morbidité et la mortalité post-opératoire. Pourtant, un certain nombre de questions restent sans réponse: la «lourdeur» du traitement en soi, la surveillance du patient, l’éducation des médecins et des infirmières, les problèmes d’éthique.

Pertes et Profits de l’Analgésie Péridurale est également l’analyse d’un bilan dont les conclusions se trouvent résumées dans ces deux mots:

  • prudence: pour que les modalités de toute nouvelle forme de traitement de la douleur ne dépasse pas ses fondements scientifiques;

  • espoir: de se donner tous les moyens, politiques, juridiques, financiers et scientifiques pour que le problème de la douleur soit pris en charge de manière globale.

Summary

Post-operative analgesis is a widely debatted subjet nowaday. Although there was a growing developpment in the knowledges of physiology and pharmacology of pain, as in the medical technology, many patients still suffer after surgery. Since many years, epidural analgesia is recognised as a potent alternative to systemic analgesia, especially in the treatment of post-operative pain. But it is important to discuss this form of analgesia in term of cost/benefit for the patient himself. Besides its well recognised quality, epidural analgesia has «second benefits» for the patient in term of positiv impact on several systems (lung function, thromboembolic disease, surgical stress, post-operative morbidity and mortality). Nevertheless some questions still remainded unanswered (epidural analgesia is a «heavy treatment», problems in relation to patient monitoring, responsability and ethic).

The assessment ofLosses and Benefits of Epidural Analgesia could be summarised in this two words:

  • caution: the application of new technologies should not pass over their scientific foundation;

  • hope: that we developp actively the political, legal, financial and scientific basis to be able to solve globally the post-operative pain problem.

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Bibliographie

  1. Bromage Ph.: The price of intraspinal narcotic analgesia: basic constraints.Anesth. analg. 60 (7), 461–463, 1991.

    Google Scholar 

  2. Kitz D.S., Slusarz-Ladden C. andLecky J.H.: Hospital ressources used for inpatient and ambulatory surgery.Anesthesiology 69, 383–386, 1988.

    Article  PubMed  CAS  Google Scholar 

  3. Vercauteren M., Meese G., Lauwers E. et al.: Addition of clonidine potentiates postoperative analgesia of epidural sufentanil.Anesth. analg. 70, 55, 1990.

    Google Scholar 

  4. Rostaing S., Bonnet F., Levron J.C. et al.: Effects of epidural clonidine on epidural analgesia and pharmacokinetics in postoperative patients.Anesthesiology 73, A 779, 1990. Perenteral morphine compared with epidural analgesia.Surgery 104 (1), 57–63, 1988.

    Article  Google Scholar 

  5. Gustavson L.L., Sheildt B. andJacobsen K.: Adverse effects of extradural and intrathecal opiates: report of a nationwide survey in Sweden.Br. J. Anaesth. 54, 479–486, 1982.

    Article  Google Scholar 

  6. Rawal N., Arner S., Gustafsson L.L. andAllvin R.: Present state of extradural and intrathecal opioid analgesia in Sweden.Br. J. Anaesth. 59, 791–799, 1987.

    Article  PubMed  CAS  Google Scholar 

  7. Maier C., Wawersik J. andWulf H.: Results of a questionnaire survey of the practice and organization of post-operative peridural abakgesua at 461 anesthesia departments.Reg. Anaesth. 14 (4), 69–69, 1991.

    Google Scholar 

  8. Saidman L.J.: The anesthesiologist outside the operating room: a new and exciting opportunity.Anesthesiology 68, 1–2, 1988.

    Article  PubMed  CAS  Google Scholar 

  9. Grigsby E.J. andCucehiara R.F.: Operating room management. Miller R.D.,Anesthesia, 3rd Edition, 2359–2360, 1992.

  10. Yeager M.P.: Epidural anaesthesia and analgesia in high risk surgical patients.Anesthesiology 66, 729–736, 1987.

    Article  PubMed  CAS  Google Scholar 

  11. Lehmann K.A., Einnolf C., Eberlein H.J. andNagel R.: Transdermal fentanyl for the treatment of pain after major urological operations: A randomized double-blind comparison with placebo using intravenous patient-controlled analgesia.Eur. J. Clin. Pharmacol. 41, 17–21, 1991.

    Article  PubMed  CAS  Google Scholar 

  12. Streisand J.B., Varvel J.R., Stanski D.R. et al.: Absorption and bioavailability of oral transmucosal fentanyl citrate.Anesthesiology 75, 223–229, 1991.

    Article  PubMed  CAS  Google Scholar 

  13. Duthie D.J.R., Rowbotham D.J., Wyld R., Henderson P.D. andNimmo W.S.: Plasma fentanyl concentrations during transdermal delivery of fentanyl to surgical patients.Br. J. Anaesth. 60, 614–618, 1988.

    Article  PubMed  CAS  Google Scholar 

  14. Huntoon M., Eisenach J.C. andBoese P.: Epidural Clonidine after Cesarean Section.Anesthesiology 76, 187–193, 1992.

    Article  PubMed  CAS  Google Scholar 

  15. Carabine U.A., Milligan K.R. andMoore J.: Extradural Clonidine and Bupivacaine for postoperative analgesia.Br. J. of Anaesthesia 68, 132–135, 1992.

    Article  CAS  Google Scholar 

  16. Reiz S., Ahlin J., Ahrenfeldt B. et al.: Epidural morphine for post-operative pain relief.Acta Anaesthesiol. Scand. 25, 111, 1981.

    PubMed  CAS  Google Scholar 

  17. Raj P.P.: Practical Management of Pain. Chicago, Yearbook Medical Publishers, 1986, p. 698.

    Google Scholar 

  18. Raj P.P., Knarr D., Vigdorth E. et al.: Comparison of continuous epidural infusion of a local anesthetic and administration of systemic narcotics in the management of pain after total knee replacement surgery.Anesth. Analg. 66, 401, 1987.

    Article  PubMed  CAS  Google Scholar 

  19. Welcheww E.A. andThornton J.A.: Continuous thoracic epidural fentanyl.Anesthesia 37, 309, 1982.

    Article  Google Scholar 

  20. Shulman M., Sandler A., Bradley J. et al.: Post-thoracotomy pain and pulmonary function following epidural and systemic morphine.Anesthesiology 61, 569, 1984.

    Article  PubMed  CAS  Google Scholar 

  21. Logas W., El-Baz N., El-Ganzouri A. et al.: Continuous thoracic epidural analgesia for postoperative pain relief following thoracotomy: A randomized prospective study.Anesthesiology 67, 787, 1987.

    Article  PubMed  CAS  Google Scholar 

  22. Rawal N., Sjostrand U.H., Dahlstrom B. et al.: Epidural morphine for postoperative pain relief: A comparative study with intramuscular narcotic and intercostal nerve block.Anesth. Analg. 61, 93, 1982.

    Article  PubMed  CAS  Google Scholar 

  23. Benhamou D., Samii K. andNoviant Y.: Effect of analgesia on respiratory muscle function after upper abdominal surgery.Acta Anaesthesiol. Scand. 27, 22, 1983.

    Article  PubMed  CAS  Google Scholar 

  24. Bromage P.R., Camporesi E. andChestnut D.: Epidural narcotics for postoperative analgesia.Anesth. Analg. 59, 473, 1980.

    Article  PubMed  CAS  Google Scholar 

  25. Torda T.A. andPybus D.A.: Comparison of four narcotic analgesics for extradural analgesia.Br. J. Anaesth. 54, 291, 1982.

    Article  PubMed  CAS  Google Scholar 

  26. Rawal N., Sjostrand U.H., Christofferson E. et al.: Comparison of intramuscular and epidural morphine for postoperative analgesia in the grossly obese: Influence on postoperative ambulation and pulmonary function.Anesth. Analg. 63, 583, 1984.

    PubMed  CAS  Google Scholar 

  27. Cuschieri R.J., Morran C.G., Howie J.C. andMc Ardie C.S.: Post-operative pain and pulmonary complications: comparison of three analgesic regimens.Br. J. Surg. 72, 495–498, 1985.

    Article  PubMed  CAS  Google Scholar 

  28. Malicier J. andJourdan C.: La responsabilité médicale.Anesthésie-Réanimation 367, 10–12, 1986.

    Google Scholar 

  29. Modig J., Borg T., Karlstrom G. et al.: Thromboembolism after total hip replacement: Role of epidural and general anesthesia.Anesth. Analg. 62, 174, 1983.

    Article  PubMed  CAS  Google Scholar 

  30. Kehlet H.: The modifying effect of general and regional anesthesia on the endocrine-metabolic response to surgery.Reg. Anesth. 7,S39, 1982.

    Google Scholar 

  31. Isaacson I.J., Weitzu F.I., Berry A.J. et al.: Intrathecal morphine’s effect on the postoperative course of patients undergoing abdominal aortic surgery.Anesth. Analg. 66, S86, 1987.

    Google Scholar 

  32. Pflug A.E., Murphy T.M., Vurlwe A.H. et al.: The effects of post-operative peridural analgesia on pulmonary complications.Anesthesiology 41, 8, 1974.

    Article  PubMed  CAS  Google Scholar 

  33. Bromage P.R.: Epidural analgesia. W.B. Saunders Company, pp. 226–228, 665–666, 1970.

  34. Ready L.B., Loper K.A., Nessly M. andWild L.: Postoperative epidural morhine is safe on surgical wards.Anesthesiology 68, 1–2, 1988.

    Article  Google Scholar 

  35. Sinatra R.S.: Current methods of controlling post-operative pain.Yale J. Biol. Med. 64 (4), 351–374, 1991.

    PubMed  CAS  Google Scholar 

  36. Whedon M. andFerrell B.R.: Professional and ethical considerations in the use of high-tech pain management.Oncol. Nurs Forum 18 (7), 1135–1143, 1991.

    PubMed  CAS  Google Scholar 

  37. Russel R.D.: A word of caution in acute pain management 5, suppl. 1, S50-S62, 1989.

    Google Scholar 

  38. Max B.M.: US Governement disseminates acute pain treatment guidelines: will they make a difference?Pain 50, 3–4, 1992.

    Article  PubMed  CAS  Google Scholar 

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Texte présenté lors du Congrès de la SOFRED des 8 et 9 octobre 1992.

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Klopfenstein, C.E. Pertes et profits de l’analgésie péridurale. Doul. et Analg. 6, 35–39 (1993). https://doi.org/10.1007/BF03019254

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