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Colites Infectieuses

Infectious colitis

  • Published:
Acta Endoscopica

Résumé

La colite infectieuse est une pathologie courante, Elle engendre habituellement des diarrhées aiguës. Le diagnostic différentiel des diarrhées aiguës comprend les infections coliques, les lésions d'origine médicamenteuse, les Maladies Inflammatoires Cryptogéniques de l'Intestin (MICI), les lésions coliques ischémiques et des désordres de type fonctionnel tels que le côlon irritable. Un diagnostic précis n'est pas toujours facile. Dans beaucoup de cas, les lésions d'origine médicamenteuse doivent être prises en compte.

Les biopsies sont d'une grande utilité dans le diagnostic non seulement de colite (diagnostic différentiel avec les désordres d'origine fonctionnelle) mais également dans le diagnostic différentiel entre les colites infectieuses et les MICI. L'aspect microscopique des colites infectieuses est très variable. Dans la majorité des cas, il n'existe pas d'aspect histologique spécifique. Le diagnostic histologique repose à la fois sur la présence d'une inflammation aiguë et sur l'absence d'aspect histologique suggestif de MICI. Quelques infections virales mycotiques ou bactériennes ont un aspect microscopique suggérant un diagnostic précis, diagnostic confirmé quand l'agent pathogène est mis en évidence sur les coupes histologiques.

Summary

Infectious-type colitis is a common condition. It usually induces acute diarrhoea. The differential diagnosis of acute diarrhoea includes injections, drug-induced lesions, chronic idiopathic inflammatory bowel diseases (IBD), ischaemic colitis and functional disorders such as irritable bowel syndrome. A precise diagnosis is not always simple. In many cases, drug-induced diseases have however to be considered.

Biopsies are considered to be very useful for the diagnosis of colitis (differential diagnosis with functional disorders) and for the differential diagnosis between infections and IBD. The microscopic features of infectious colitis are highly variable. In the majority of cases, there is no specific pattern. The diagnosis relies mainly on the presence of active inflammation and the absence of features suggestive for IBD. Some viral, fungal or bacterial infections lead to specific microscopic features allowing a diagnosis especially when the pathogenic agents are evident on histological slides.

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Références

  1. MEUWISSEN S.G.M., VANDENBROUCKE-GRAULS C.M.J., GEBOES K. — Spectrum of acute self-limiting colitis: role of the clinician and pathologist.Ital. J. Gastroenterol. Hepatol., 1999,31, 807–816.

    PubMed  CAS  Google Scholar 

  2. SIPROUDHIS L., MAHMOUD H., BRIAND N., JUGUET F., BRETAGNE J.F., ALAIN H. — Responsabilité des médicaments dans la survenue des colites aiguës.Gastroenterol. Clin. Biol., 1998,22, 778–784.

    PubMed  CAS  Google Scholar 

  3. MARTIN P., MANLEY N., DEPEW W.T., BLAKEMAN J.M. — Isotretinoin-associated proctosigmoiditis.Gastroenterol., 1987,93, 606–609.

    CAS  Google Scholar 

  4. MORIARTY K.J., TURNBERG I.A. — Bacterial toxins and diarrhoea.Cli. in Gastroenterol., 1986,15, 529–543.

    CAS  Google Scholar 

  5. JONES N.L., PHILPOTT D.J., SHERMAN P.M. — Gastrointestinal infections in children.Current opinion in Gastroenterology, 1998,14, 70–76.

    Article  Google Scholar 

  6. NOSTRANT T., KUMAR N.B., APPELMAN H.D. — Histopathology differentiates acute self-limited colitis from ulcerative colitis.Gastroenterol., 1987,92, 318–328.

    CAS  Google Scholar 

  7. RUTGEERTS P., GEBOES K., PONETTE E., COREMANS G., VANTRAPPEN G. — Acute infective colitis caused by endemic pathogens in Western Europe: endoscopic features.Endoscopy, 1982,14, 212–219.

    Article  PubMed  CAS  Google Scholar 

  8. DUNDAS S.A.C., DUTTON J., SKIPWORTH P. — Reliability of rectal biopsy in distinguishing between chronic inflammatory bowed disease and acute self-limiting colitis.Histopathology, 1997,31, 60–66.

    Article  PubMed  CAS  Google Scholar 

  9. JENKINS D., BLASITIS M., GALLIVAN S., DIXON M.F., GILMOUR H.M., SHEPHERD N.A., THEODOSSI A., WILLIAMS G.T. — Guidelines for the initial biopsy diagnosis of suspected chronic idiopathic inflammatory bowel disease. The British Society of Gastroenterology Initiative.J. Clin. Pathol., 1997,50, 93–105.

    Article  PubMed  CAS  Google Scholar 

  10. VAN SPREEUWEL J.P., DUURSMA G.C., MEIJER C.J.L.M., BAX R., ROSEKRANS P.C.M., LINDEMAN J. —Campylobacter colitis: histological, immunohistochemical and ultrastructural findings.Gut, 1985,26, 945–951.

    Article  PubMed  Google Scholar 

  11. LJUNGH A. — Bacterial infections of the small intestine and colon.Current opinion in Gastroenterology, 1998,14, 33–44.

    Article  Google Scholar 

  12. ROTHBAUM R., McADAMS A.J., GIANELLA R., PARTIN J.C. — A clinicopathological study of enterocyte-adherentEscherichia coli: a cause of protracted diarrhoea in infants.Gastroenterol., 1982,83, 441–454.

    CAS  Google Scholar 

  13. GRIFFIN P.M., OLMSED L.C., PETRAS R.E. —Escherichia coli 0157/h7-associated colitis: a clinical and histological study of 11 cases.Gastroenterol., 1990,99, 142–149.

    CAS  Google Scholar 

  14. KELLY J.K., PAI C.H., JADUSINGH I.H., MACINNIS M.L., SHAFFER E.A., HERSHFIELD N.B. — The histopathology of rectosigmoid biopsies from adults with bloody diarrhoea due to verotoxin-producingEscherichia coli.Am. J. Clin. Pathol., 1987,88, 78–82.

    PubMed  CAS  Google Scholar 

  15. MORRISON D.M., TYRRELL D.L.J., JEWELL L.D. — Colonic biopsy in verotoxin-induced hemorrhagic colitis and thrombocytopenic purpura.Am. J. Clin. Pathol., 1986,86, 108–112.

    PubMed  CAS  Google Scholar 

  16. MANDAL B.K. — Bacterial infections: typhoid fever and other salmonella infections.Current opinion in Gastroenterology, 1985,1, 138–142.

    Article  Google Scholar 

  17. KATAKURA S., REINHOLT F.P., KARNELL A., HUAN P.T., TRACH D.D., LINDBERG A.A. — The pathology ofShigella flexneri infection in Rhesus Monkeys: an endoscopic and histopathological study of colonic lesions.APMIS, 1990,98, 313–319.

    PubMed  CAS  Google Scholar 

  18. VANTRAPPEN G., PONETTE E., GEBOES K., BERTAND P. —Yersinia enteritis and enterocolitis: gastroenterological aspects.Gastroenterol., 1977,72, 220–227.

    CAS  Google Scholar 

  19. VANTRAPPEN G., GEBOES K., PONETTE E. —Yersinia enteritis. Med. Clin. North Am., 1982, 66, 639–653.

    PubMed  CAS  Google Scholar 

  20. LARSON H.E., PRICE A.B. —Pseudomembranous colitis: presence of clostridial toxin.Lancet, 1977,ii, 1312–1314.

    Article  Google Scholar 

  21. REINKE C.M., MESSICK C.R. — Update onC. difficile-induced colitis.Am. J. Hosp. Pharm., 1994,51, 14–19.

    Google Scholar 

  22. PRICE A.B., DAVIES D.R.D. —Pseudomembranous colitis.J. Clin. Pathol., 1977,30, 1–12.

    Article  PubMed  CAS  Google Scholar 

  23. MARSH P.K., GORBACH S.L. — Invasive enterocolitis caused byEdwardsiella tarda.Gastroenterol., 1982,82, 336–338.

    CAS  Google Scholar 

  24. MAANDAL B.K., WHALE K., MORSON B.C. — Aeute colitis due toPlesiomonas shigelloides.Br. Med. J., 1982,285, 1539–1540.

    Article  Google Scholar 

  25. DELLADETSIMA K., MARKAKI S., PAPADIMITRIOU K., ANTONAKOPOULOS G.N. — Intestinal Spirochetosis: light and electron microscopic study.Path. Res. Pract., 1987,182, 780–782.

    PubMed  CAS  Google Scholar 

  26. KUNKEL J.M., ROSENTHAL D. — Management of the ileocecal syndrome.Dis. Colon Rectum, 1986,29, 196–199.

    Article  PubMed  CAS  Google Scholar 

  27. YEONG M.L., NICHOLSON G.I. — Clostridium septicum infection in neutropenic enterocolitis.Pathology, 1988,20, 194–197.

    Article  PubMed  CAS  Google Scholar 

  28. MULLHOLLAND M.W., DELANEY J.P. — Neutropenic colitis and aplastic anemia: a new association.Ann. Surg., 1983,197, 84–90.

    Google Scholar 

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Jouret-Mourin, A., Geboes, K. Colites Infectieuses. Acta Endosc 32, 167–183 (2002). https://doi.org/10.1007/BF03016654

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  • DOI: https://doi.org/10.1007/BF03016654

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