Summary and Conclusions
Meprobamate was used orally, early in labour, for relaxation of seventy-four patients (fifty primiparas, twenty-four multiparas). Emotional tension was relieved in a significant proportion of patients. The findings in this study would seem to indiçate that the compound should be used for the express purpose of allaying the anxiety and apprehension attendant upon the early phases of the first stage, prior to the need of analgesia. Meprobamate is neither an analgesic, nor a potentiator of analgesics.
Meprobamate appears to have no deleterious effect on the mechanism of parturition or on the foetus, one patient exhibited cutaneous evidences of sensitivity. Labour proceeded normally, however, and the infant was delivered safely.
Résumé
Chez soixante-quatorze malades (cinquante primipares et vingt-quatre multipares) dans le but ďobtenir du relâchement, nous avons employé, au début du travail, du meprobamate per os. Dans une proportion importante des malades, la tension émotionnelle a été vaincue.
Les résultats de cette étude nous amènent à croire que ce médicament ne devrait être employé que dans un but précis: diminuer ľanxiété et ľapprénension des premiers moments du travail avant que ľanalgésie; ne soit reduise. Lemeprobamate n’est ni un analgésique ni un potentialisateur des analgésiques.
Le meprobamate, toutefois, ne semble pas avoir ďeffets nuisibles sur le fœtus ni sur les mécanismes du travail. Une malade sensible au médicament a présenté des manifestations cutanées. Toutefois, le travail s’est poursuivi normalement et ľenfant est né sans signe de séquelles.
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Carroll, J.J., Moir, R.S. An investigation of ataraxics in labour: meprobamate (equanil®). Canad. Anaesth. Soc. J. 6, 153–158 (1959). https://doi.org/10.1007/BF03014212
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DOI: https://doi.org/10.1007/BF03014212