Skip to main content
Log in

Obésité, diabète de type 2 et prédisposition génðique

  • Dossier
  • Published:
BioTribune Magazine

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Bibliographie

  1. Ziegler O, Debry G. Épidémiologie des obésités de l’adulte. Encl Med Chir. 1998;10-506-B:7p.

  2. Haffner SM. Epidemiology of type 2 diabetes: risk factors. Diabetes Care. 1998;21, suppl 3:C3-C6.

    PubMed  Google Scholar 

  3. Leong KS, Wilding JP. Obesity and diabetes. Baillere’s Clin Endoc & Metab. 1999;13:221–237.

    CAS  Google Scholar 

  4. Perusse L. Genetics of human obesity: results from genetic epidemiology studies. Ann Endocrinol (Paris). 2000;61 suppl 6:24–30.

    Google Scholar 

  5. Boutin P, Froguel P. Genetics of human obesity. Best Pract & Research Clin Endocrinol & Metab. 2001;15:391–404.

    Article  CAS  Google Scholar 

  6. Farooqi IS, Yeo GS, Keogh JM, al. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. J Clin Invest. 2000;160:271–279.

    Article  Google Scholar 

  7. Vaisse C, Clement K, Durand E, Hercberg S, Guy-Grand B, Froguel P. Melanocortin -4 receptor mutations are frequent and heterogenous cause of morbid obesity. J Clin Invest. 2000;106:253–252.

    Article  PubMed  CAS  Google Scholar 

  8. Havel PJ. Role of adipose tissue in body-weight regulation: mechanisms regulating leptin production and energy balance. Proc Nutr Soc. 2000;59:359–371.

    Article  PubMed  CAS  Google Scholar 

  9. Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature. 2000;405:421–424.

    Article  PubMed  CAS  Google Scholar 

  10. Sorensen TIA, Echwald SM. Obesity genes. Identifying single genes involved in polygenic inheritance is not easy. BMJ. 2001;322:630–631.

    Article  PubMed  CAS  Google Scholar 

  11. Prentice AM, Jebb SA. Obesity in Britain: gluttony or sloth? Bmj. 1995;311(7002):437–9.

    PubMed  CAS  Google Scholar 

  12. Bouchard C, Pérusse L. Gene diet interactions in obesity. Am J Clin Nutr. 2000;72:1285S-1290S.

    PubMed  Google Scholar 

  13. Rissanen AM, Heliovaara M, Knekt P, Reunanen A, Aromaa A, al. Determinants of weight gain and overweight in adults Finns. Eur J Clin Nutr. 1991;45:419–430.

    PubMed  CAS  Google Scholar 

  14. Basdevant A, Le Barzic M, Guy-Grand B. Les obésitées. In: Basdevant A, Laville M, Lerebours E, eds. Traité de nutrition clinique de l’adulte. Juin 2001 ed. Paris: Medecine-Science Flamarion; 2001:429–450.

    Google Scholar 

  15. Bouchard C, Tremblay A, Despres JP, et al. The response to long-term overfeeding in identical twins. N Engl J Med. 1990;322(21):1477–82.

    PubMed  CAS  Google Scholar 

  16. Bouchard C, Tremblay A, Despre JP, al. The response to exercise with constant energy intake in identical twins. Obes Res. 1994;2:400–410.

    PubMed  CAS  Google Scholar 

  17. Valencia ME, Bennett PH, Ravussin E, Esparza J, Fox C, Schulz LO. The Pima Indians in Sonora, Mexico. Nutr Rev. 1999;57(5 Pt 2):S55–7; discussion S57–8.

    Article  PubMed  CAS  Google Scholar 

  18. Hu FB, Manson JE, Stampfer MJ, et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med. 2001;345(11):790–7.

    Article  PubMed  CAS  Google Scholar 

  19. Östenson CG. The pathophysiology of type 2 diabetes mellitus: an overview. Acta Physiol Scand. 2001;171:241–247.

    Article  PubMed  Google Scholar 

  20. Diabetes Prevention Programm Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393–403.

    Article  Google Scholar 

  21. Frogel P. Genetics of type II diabetes. Arch Mal coeur. 2000;93:7–12.

    Google Scholar 

  22. Ducluzeau P-H, Peretti N, Laville M, et al. Regulation by insulin of gene expression in human skeletal muscle and adipose tissue. Evidence for specific defects in type 2 diabetes. Diabetes. 2001;50:1134–1142.

    Article  PubMed  CAS  Google Scholar 

  23. Gerich JE. Insulin resistance is not necessarily an essential component of type 2 diabetes. J Clin Endocrinol Metab. 2000;85:2113–2114.

    Article  PubMed  CAS  Google Scholar 

  24. Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest. 1999;104(6):787–94.

    Article  PubMed  CAS  Google Scholar 

  25. Masuzaki H, Paterson J, Shinyama H, et al. A transgenic model of visceral obesity and the metabolic syndrome. Science. 2001;294:2166–2170.

    Article  PubMed  CAS  Google Scholar 

  26. Dabelea D, Hanson RL, Lindsay RS, et al. Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships. Diabetes. 2000;49(12):2208–11.

    Article  PubMed  CAS  Google Scholar 

  27. Frayn KN. Adipose tissue and the insulin resistance syndrome. Proc Nutr Soc. 2001;60(3):375–80.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rabasa-Lhoret, R., Froguel, P. Obésité, diabète de type 2 et prédisposition génðique. Bio trib. mag. 2, 35–39 (2002). https://doi.org/10.1007/BF03013600

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03013600

Navigation