Abstract
Serum potassium levels were measured in 15 patients with brain tumours between 3–7 cm diameter, during thiopentone/70 per cent N2O in O2 anaesthesia, with mask ventilation controlled to maintain a constant end-tidal CO2 concentration. Potassium levels were determined one minute before and one and ten minutes after administration of succinylcholine 1.0mg·kg−1 IV. No statistically significant increase in serum potassium occurred following succinylcholine, nor were there any ECG changes associated with succinylcholine administration. Use of succinylcholine in patients with brain tumours does not appear to cause elevation of serum potassium levels or ECG changes.
Reésumé
Chez 15 patients présentant des tumeurs cérébrates de 3–7 cm de diamètre, le potassium serique a été mesuré lors d’ une anesthésie avec le thiopentonel 70 pour cent de protoxyde d’azote et oxygène en normocarbie utilisant une ventilation contrôlée au masque. Le potassium sérique a été déterminé une minute avant et une et dix minutes après l’administration de la succinylcholine 1 mg·kg−1 en injection intraveineuse. Aucune augmentation statistiquement significative du potassium seérique n’est survenue après succinylcholine et aucun changement de l’ECG ne fut associé à l’administration de succinylcholine. L’utilisation de la succinylcholine chez les patients présentant des tumeurs cérébrates n ’apparaît pas comme étant la cause a’une élévation du potassium sérique ni des changements à l’ECG.
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Minton, M.D., Stirt, J.A. & Bedford, R.F. Serum potassium following succinylcholine in patients with brain tumours. Can Anaesth Soc J 33, 328–331 (1986). https://doi.org/10.1007/BF03010745
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DOI: https://doi.org/10.1007/BF03010745