Summary
Oxygen gas was repeatedly insufflated into the isolated colon of a patient with severe chronic ulcerative colitis. The treatment was given for periods varying from 2 to 12 hours over a time interval of 112 days. During this time 43 bacteriological examinations were made of the colon and its discharges. The isolated diseased colon failed to heal andBacterium necrophorum continued present and was found in abundance, especially during periods when the diseased process appeared aggravated.
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Dack, G.M., Dragstedt, L.R. Effect of introducing oxygen into the isolated colon of a patient with chronic ulcerative colitis. American Journal of Digestive Diseases 5, 84–86 (1938). https://doi.org/10.1007/BF03010599
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DOI: https://doi.org/10.1007/BF03010599