Abstract
This case report describes the use of octreotide, a long-acting somatostatin analogue, in the management of a patient with an ovarian carcinoid tumour and severe cardiac valvular disease. This patient underwent laparotomy and tumour resection without complication. Anaesthesia was induced with midazolam, fentanyl, and vecuronium, and maintained with isoflurane as well as additional fentanyl and vecuronium. However, we feel that it was the use of octreotide that prevented a life-threatening crisis intraoperatively, and recommend its use in patients with carcinoid syndrome undergoing anaesthesia and surgery.
Résumé
Cette histoire de cas décrit l’utilisation de l’octréotide, un analogue à longue action de la somatostatine, dans le traitement d’une patiente présentant une tumeur ovarienne carcinoide et une maladie cardiaque valvulaire sévère. Cette patiente a subi une laparotomie et une résection de la tumeur sans complication. L’anesthésie fut induite avec le midazolam, fentanyl et vécuronium et maintenue avec l’isoflurane et des doses additionnelles de fentanyl et de vécuronium. Cependant, on pense que l’utilisation de l’octréotide a empêché les problèmes peropératoires et on recommande son utilisation chez les patientes ayant un syndrome carcinoïde et devant subir une anesthésie et une chirurgie.
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Watson, J.T., Badner, N.H. & Ali, M.J. The prophylactic use of octreotide in a patient with ovarian carcinoid and valvular heart disease. Can J Anaesth 37, 798–800 (1990). https://doi.org/10.1007/BF03006540
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DOI: https://doi.org/10.1007/BF03006540