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Anaesthesia for renal transplantation in sickle cell disease

Canadian Journal of Anaesthesia volume 37, pages 778–785 (1990)Cite this article

Abstract

Sickle cell disease (SCD) is associated with many pathological and functional abnormalities affecting all organ systems. Renal manifestations of SCD may result in end-stage renal disease (ESRD), which can be treated by chronic haemodialysis or renal transplantation. Renal transplantation was successfully performed in a 25-yr-old male with sickle cell beta-thalassaemia and nephrotic syndrome. We present a case report of this patient, a discussion of the renal complications associated with SCD and the perioperative management of a patient with SCD undergoing renal transplantation.

Résumé

L’anémie falciforme peut entrainer une myriade d’anomalies fonctionnelles el pathologiques impliquant tous les systèmes avec entre autres, de l’insuffisance rénale chronique sévère. Nous vous présentons un cas de transplantation rénale réussie chez un homme de 25 ans atteint d’un syndrome néphrotique avec une hémoglobinopathie de type Sβ-thal. Nous discutons de l’impact de l’anémie falciforme sur la fonetion rénale et des considérations péri-opératoires propres à la transplantation rénale chez ce type de patient.

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Affiliations

  1. Department of Anaesthesia, The Royal Hospital, P.O. Box 2331, Seeb Muscat, Sultanate of Oman

    Henry K. Gyasi, A. W. Zarroug, M. Matthew, R. Joshi & A. Daar

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  1. Henry K. Gyasi
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  2. A. W. Zarroug
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  3. M. Matthew
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  4. R. Joshi
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Gyasi, H.K., Zarroug, A.W., Matthew, M. et al. Anaesthesia for renal transplantation in sickle cell disease. Can J Anaesth 37, 778–785 (1990). https://doi.org/10.1007/BF03006536

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Key words

  • anaesthesia: transplantation
  • blood: anaemia, sickle cell disease
  • kidney: failure, transplantation