Abstract
A 53-year-old male patient with a previous diagnosis of situs inversus with mirror-image dextrocardia underwent thallium-201 (Tl-201) stress-redistribution myocardial perfusion single photon emission computed tomography (SPECT). Electrocardiogram (ECG) obtained on right hemithorax revealed constant complete left bundle branch block. Tl-201 stress-redistribution SPECT images revealed abnormal perfusion with reversible ischemia in the anteroseptal, septal and inferoseptal walls. Coronary angiography performed 1 month after SPECT study was normal. This case illustrates that false positive reversible perfusion defects can be seen in patients with mirror-image dextrocardia associated with constant complete left bundle branch block. To our knowledge, this is the first reported case of mirror-image dextrocardia and constant complete left bundle branch block with false positive Tl-201 SPECT findings.
Similar content being viewed by others
References
Schlant RC, Alexander RW. The pathology, pathophysiology, recognition, and treatment of congenital heart disease. Congenital Heart Disease. Chapter 97, Part XI. In:Hurst’s the Heart (8th ed). McGraw Hill, Inc., 1994: 1806–1808.
Raju R, Singh S, Kumar P, Rao S, Kapoor S, Raju BS. Percutaneous balloon valvuloplasty in mirror-image dextrocardia and rheumatic mitral stenosis.Cathet Cardiovasc Diagn 1993; 30: 138–140.
Raines KH, Armstrong BE. Aortic atresia with visceral situs inversus with mirror-image dextrocardia.Pediatr Cardiol 1989; 10: 232–235.
Ilia R, Gussarsky Y, Gueron M. Coronary angiography in a patient with mirror-image heart (situs inversus).Int J Cardiol 1988; 20: 273–275.
Florez M, Attie F, Munoz-Castellanos L, Vargas Barron J, Ovseyevitz J, Buendia A, et al. Double inlet left ventricle.Arch Inst Cardiol Mex 1986; 56: 63–69.
Attie F, Ovseyevitz J, Llamas G, Buendia A, Vargas J, Munoz L. The clinical features and diagnosis of a discordant atrioventricular connection.Int J Cardiol 1985; 8: 395–419.
Dunseath R, Williams W, Patton D. A scintigraphic demonstration of dextrocardia and complete abdominal situs inversus.Clin Nucl Med 1990; 15: 501–503.
Wester JP, Ernst JM, Mast EG, Plokker HW, Bal ET, Verzijlbergen JF. Coronary angioplasty in a patient with situs inversus totalis and a single coronary artery.Cathet Cardiovasc Diagn 1994; 31: 304–308.
DeLong SR. Thallium stress test in a patient with dextrocardia.Clin Nucl Med 1983; 8: 180.
Kasner JR, Kamrani F. Thallium imaging in a patient with situs inversus.Clin Nucl Med 1983; 8: 224.
Davidson A, Luhmer I, Kallfelz HC. Right sided heart with mirror-image atrial arrangement, complete transposition, ventricular septal defect and subpulmonary stenosis.Int J Cardiol 1989; 22: 264–267.
Yamazaki T, Tomaru A, Wagatsuma K, Kudo M, Baba J, Takikawa K, et al. Percutaneous transluminal coronary angioplasty for morphologic left anterior descending artery lesion in a patient with dextrocardia. A case report and literature review.Angiology 1997; 48: 451–456.
Hasegawa S, Sakata Y, Ishikura F, Hirayama A, Kusuoka E, Nishimura T, et al. Mechanism for abnormal thallium-201 myocardial scintigraphy in patients with left bundle branch block in the absence of angiographic coronary artery disease.Ann Nucl Med 1999; 13: 253–259.
Skalidis EI, Kochiadakis GE, Koukouraki SI, Parthenakis FI, Karkavitsas NS, Vardas PE. Phasic coronary flow pattern and flow reserve in patients with left bundle branch block and normal coronary arteries.J Am Coll Cardiol 1999; 33: 1388–1346.
Campeau RJ, Garcia OM, Colon R, Agusala M, Correa OA. False-positive Tc-99m sestamibi SPECT in a patient with left bundle branch block.Clin Nucl Med 1993; 18: 40–42.
Peng NJ, Mar GY, Liu CP, Jao GH, Lee D, Liang HL, et al. Does inadequate exercise lower the accuracy of myocardial perfusion scintigraphy?Nucl Med Commun 2001; 22: 625–629.
Ellmann A, VanHeerden PD, VanHeerden BB, Klopper JF. Tc-99m MIBI stress-rest myocardial perfusion scintigraphy in patients with complete left bundle branch block.Cardiovasc J S Afr 2001; 12: 252–256.
Vaduganathan P, He ZX, Raghavan C, Mahmarian JJ, Verani MS. Detection of left anterior descending coronary artery stenosis in patients with left bundle branch block: exercise, adenosine or dobutamine imaging?J Am Coll Cardiol 1996: 28: 543–550.
Altehoefer C, Vom Dahl J, Kleinhans E, Uebis R, Hanrath P, Buell U. Tc-99m-methoxyisobutylisonitrile stress/rest SPECT in patients with constant complete left bundle branch block.Nucl Med Commun 1993; 14: 30–35.
Candell-Riera J, Oller-Martinez G, Rossello J, Pereztol-Valdes O, Castell-Conesa J, Aguade-Bruix S, et al. Standard provocative manoeuvres in patients with and without left bundle block studied with myocardial SPECT.Nucl Med Commun 2001; 22: 1029–1036.
Richter WS, Aurisch R, Munz DL. Septal myocardial perfusion in complete left bundle branch block: case report and review of the literature.Nuclearmedizin 1998; 37: 146–150.
Wagdy HM, Hodge D, Christian TF, Miller TD, Gibbons RJ. Prognostic value of vasodilator myocardial perfusion imaging in patients with left bundle branch block.Circulation 1998; 97: 1563–1570.
Nigam A, Humen DP. Prognostic value of myocardial perfusion imaging with exercise and/or dipyridamole hyperemia in patients with preexisting left bundle branch block.J Nucl Med 1998; 39: 579–581.
Lebtahi NE, Stauffer JC, Delaloye AB. Left bundle branch block and coronary artery disease: accuracy of dipyridamole thallium-201 single photon emission computed tomography in patients with exercise anteroseptal perfusion defects.J Nucl Cardiol 1997; 4: 266–273.
Hesse B, Kjaer A. Stress test and myocardial perfusion scintigraphy. [Editorial]Nucl Med Commun 2001; 22: 851–855.
Inanir S, Caymaz O, Okay T, Dede F, Oktay A, Deger M, et al. Tc-99m Sestamibi gated SPECT in patients with left bundle branch block.Clin Nucl Med 2001; 26: 840–846.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Turgut, B., Kitapci, M.T., Temiz, N.H. et al. Thallium-201 myocardial SPECT in a patient with mirror-image dextrocardia and left bundle branch block. Ann Nucl Med 17, 503–506 (2003). https://doi.org/10.1007/BF03006443
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF03006443