Summary
One hundred female patients were studied, who were premedicated with atropine alone and anaesthetized with ketamine 2.0 mg/Kg as the sole agent for minor gynaecological procedures. Fifty of these patients received thiopentone sodium 150 mg intravenously at the end of the operation. The incidence and severity of emergence reactions was significantly less in this group of patients than in the group that had no thiopentone. The dose of thiopentone employed did not produce respiratory depression.
Résumé
Au cours d’opérations gynécologiques mineures, on a employé la Kétamine (2.0 mg/kg) comme seul agent anesthésique chez cent (100) patientes préalablement prémédiquées à l’Atropine.
A la fin de l’intervention, cinquante (50) d’entre elles reçurent 150 mg de Thiopentone par voie endoveineuse. L’étude comparée des deux groupes a montré une réduction significative du nombre et de la gravité des réactions psychiâtriques d’émergence.
Aux doses utilisées, le Thiopentane n’a pourtant aucun effet indésirable sur la respiration.
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Magbagbeola, J.A.O., Thomas, N.A. Effect of thiopentone on emergence reactions to ketamine anaesthesia. Canad. Anaesth. Soc. J. 21, 321–324 (1974). https://doi.org/10.1007/BF03005737
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DOI: https://doi.org/10.1007/BF03005737