Abstract
The haemodynamic responses to laryngoscopy and intubation after induction of anaesthesia with thiopentone alone or in combination with 1.5 mg · kg−1 IV lidocaine were measured in 125 children age 2 to 12 yr to determine whether lidocaine administered one, two, three or four minutes before tracheal intubation attenuated the pressor response. Lidocaine did not attenuate the increases in heart rate and arterial blood pressure. The pressor response was significantly affected by baseline haemodynamic values, P < 0.05. The increases in systolic and mean blood pressure were significantly affected by the age of the patient, P < 0.05. Lidocaine is not a beneficial adjunct to induction of anaesthesia with thiopentone in healthy children for the purpose of attenuating the pressor response to intubation.
Résumé
Les réponses hémodynamiques à la laryngoscopie et l’intubation après induction de l’anesthésie avec du thiopentone seul ou en combinaison avec 1.5 mg · kg−1 IV de lidocaïne furent mesurées chez 125 enfants âgés de 2 à 12 ans afin de déterminer si la lidocaïne administrée un, deux, trots ou quatre minutes avant l’intubation trachéale atténue la réponse vasopressive. La lidocaïne n’a pas atténué l’augmentation de la fréquence cardiaque et de la pression artérielle. La réponse vasopressive était significativement affectée par les valeurs hémodynamiques de base, P < 0.05. L’augmentation de la pression artérielle systolique et de la pression artérielle moyenne était significativement affectée par l’âge du patient, P < 0.05. La lidocaïne n’est pas bénéfique lors de l’induction de l’anesthésie au thiopentone chez des enfants en bonne sauté pour atténuer la reponse vasopressive de l’intubation.
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Splinter, W.M. Intravenous lidocaine does not attenuate the haemodynamic response of children to laryngoscopy and tracheal intubation. Can J Anaesth 37, 440–443 (1990). https://doi.org/10.1007/BF03005623
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DOI: https://doi.org/10.1007/BF03005623