Abstract
In order to détérmine correlations between electromyographic (EMG), mecanomyographic (MMG) and clinical criteria of adequate recovery from neuromuscular blockade with vecuronium, seven young healthy conscious volunteers were given subparalysing doses of vecuronium. During recovery from neuromuscular blockade, vital capacity, negative inspiratory pressure, peak expiratory flow rate and five-second head lift were assessed. Neuromuscular monitoring included the evoked EMG response of the adductor digiti minimi and the simultaneous evoked MMG response of the adductor pollicis on the same side. We found that all subjects maintained head lift for five seconds at EMG T4T1 of 0.70, and they achieved normal respiratory tests at EMG T4/T1 of 0.90. The MMG T4/T1 needed for the subjects to perform normal respiratory tests was found to be 0.50, at which time six of the seven subjects were able to perform adequately the head lift test.
Résumé
La correlation entre l’électromyographie (EMG), la mécano-myographie (MMG) et des critères cliniques de récuperation adéquate suite à l’administration de doses sous-paralytisantes de vécuronium a été étudiée chez sept jeunes volontaires sains. Pendant la phase de récupération du bloc neuromusculaire, la capacité vitale, la force inspiratoire, le débit expiratoire de pointe et la capacité de maintien de la tête soulevée pour cinq secondes ont été évalués. Le monitorage neuromusculaire comprenait au niveau d’un même membre supérieur un EMG de l’adductor digiti minimi et un MMG de l’adductor pollicis. En ce qui a trait à l’EMG, tous les sujets ont réussi l’épreuve du maintien de la tête soulevée pour cinq secondes lorsque le rapport T4/T1 était de 0,70 et les tests de fonction respiratoire se sont avérés dans les limites normales lorsque le rapport T4/T1 était revenu à 0,90. Quant au MMG, six des sept sujets ont réussi le test du maintien de la tête soulevée pour cinq secondes lorsque le rapport T4/T1 etait de 0,50, alors que tous les tests de fonction respiratoire étaient revenus à la normale à ce momentlà.
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Dupuis, J.Y., Martin, R. & Tétrault, J.P. Clinical, electrical and mechanical correlations during recovery from neuromuscular blockade with vecuronium. Can J Anaesth 37, 192–196 (1990). https://doi.org/10.1007/BF03005468
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DOI: https://doi.org/10.1007/BF03005468