Summary
Plasma fluoride levels were measured in 106 patients undergoing labour and delivery or Caesarean section. Mean plasma fluoride levels in all groups of patients studied were well below the levels expected to produce renal impairment. In one case with probable excessive methoxyflurane use, plasma fluoride level reached 73.4 μmol/1. Umbilical venous fluoride levels were about one-half the mother’s venous level at delivery.
Résumé
Les niveaux plasmatiques de fluorures ont été mesurés chez 106 patientes au cours du travail et de l’accouchement ou de la césarienne. Dans tous les groupes de patientes étudiées, les niveaux moyens de fluorures plasmatiques étaient bien inférieurs aux niveaux susceptibles de provoquer une déficience rénale. Cependant dans un cas où l’emploi de méthoxyflurane semble avoir été excessif, le niveau plasmatique de fluorures a atteint 73.4 μmol/1. Les taux de fluorures dans la veine ombilicale étaient d’environ la moitié de ceux trouvés dans le sang de la mère au moment de l’accouchement.
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Palahniuk, R.J., Cumming, M. Plasma fluoride levels following obstetrical use of methoxyflurane. Canad. Anaesth. Soc. J. 22, 291–297 (1975). https://doi.org/10.1007/BF03004838
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DOI: https://doi.org/10.1007/BF03004838