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Serum ionised calcium determination by ion specific electrode, and its value in clinical metabolic disorders

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Summary

Amethod is described for determination of serum ionised calcium, using an ion specific electrode. Values recorded in 24 normal subjects, and in various disease states are presented and the clinical value of this measurement discussed.

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References

  • Burr, R. G. 1969. An automated method for serum calcium utilizing ethylene diamine tetraacetic acid. Clin. Chem. 15, 1191.

    PubMed  CAS  Google Scholar 

  • Hansen, S. O., Theodorsen, L. 1971. The userulness of an improved calcium electrode in the measurement of ionised calcium in serum. Clin Chim. Acta. 31, 119.

    Article  PubMed  CAS  Google Scholar 

  • Hattner, R. S., Johnson, J. W. Bernstein, D. S. Wachman, A. and Brackman, J. 1970. Electrochemical determination of apparent ionised serum calcium using a calcium selective electrode. The method and values in normal humans and a comparison to total serum calcium. Clin. Chim. Acta. 28, 67.

    Article  PubMed  CAS  Google Scholar 

  • Ladenson, J. H., Bowers, G. N. 1973. Free calcium serum. Rigor of homeostatic control, correlations with total serum calcium, and review of data on patients with disturbed calcium metabolism. Clin. Chem. 19, 575.

    PubMed  CAS  Google Scholar 

  • Lindegarde, R. and Zettervall, O. 1971. Serum ionised calcium in a normal population studied with a calcium ion-sensitive electrode. Israel J. Med. Sci. 7, 510.

    Google Scholar 

  • Low, J. C., Schaaf, M., Earll, J. M., Piechocki, J. T. and Ting-Kai, Li. 1973. Ionic calcium determination in primary hyperparathyroidism. J. Amer. med. Assn. 223, 152.

    Article  CAS  Google Scholar 

  • Moore, E. W. 1970. Ionised calcium in normal serum, ultrafiltrates and whole blood determined by ion-exchange electrodes. J. Clin. Invest. 49, 318.

    Article  PubMed  CAS  Google Scholar 

  • Muldowney, F. P., Carroll, D. V., Donohoe, J. F., Freaney, R. 1971. Correction of renal bicarbonate wastage by parathyroidectomy. Quart. J. Med. 40, 1.

    Google Scholar 

  • Muldowney, F. P., Freaney, R., Spillane, A., O'Donohoe, P. 1973. Ionised calcium levels in “normocalcaemic” hyperparathyroidism. I. J. med. Sci 142, 223.

    Article  CAS  Google Scholar 

  • Raman, A. 1970. Determination of ionised calcium in serum with a calcium electrode. Biochemical Medicine. 3, 369.

    Article  PubMed  CAS  Google Scholar 

  • Ross, J. W. 1967. Calcium-selective electrode with liquid ion exchanger. Science, 156, 1378.

    Article  PubMed  CAS  Google Scholar 

  • Rushtow, M. L., Sammons, H. G., Gosling, P. and Robinson, B. H. 1973. Measurement of total, ultrafiltratable and ionised serum calcium. Ann. Clin. Biochem. 10, 63.

    Google Scholar 

  • Schwartz, H. D., McConville, B. C. and Christopherson, E. F., 1971. Serum ionised calcium by specific ion electrode. Clin. Chim. Acta. 31, 97.

    Article  PubMed  CAS  Google Scholar 

  • Seamonds, B., Towfigh, J. and Arven, D. 1972. Determination of ionised calcium in serum by use of an ion-selective electrode. Clin. Chem. 18, 155.

    PubMed  CAS  Google Scholar 

  • Subryan, V. L. Popovtzer, M., Parks, S. D. and Reeve, E. B. 1972. Measurement of serum ionised calcium with the ion-exchange electrode. Clin. Chem. 18, 1459.

    PubMed  CAS  Google Scholar 

  • Ting-Kai Li and Piechocki, J. T. 1971. Determination of serum ionic calcium with an ion-selective electrode: evaluation of methodology and normal values. Clin. Chem. 17, 411.

    PubMed  CAS  Google Scholar 

  • Wills, M. R. 1971. Values of plasma chloride concentration and acid-base status in the differential diagnosis of hyperparathyroidism from other causes of hypercalcaemia. J. Clin Path. 24, 219.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. The Departments of Metabolism and Electronics, St. Vincent's Hospital, Dublin

    Rosemarle Freaney, Pauline O'Donohoe, Richard Bergin, John Bernard, Gillian Maughan & Francis P. Muldowney

  2. the Department of Medicine, University College, Dublin

    Rosemarle Freaney, Pauline O'Donohoe, Richard Bergin, John Bernard, Gillian Maughan & Francis P. Muldowney

Authors
  1. Rosemarle Freaney
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  2. Pauline O'Donohoe
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  3. Richard Bergin
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  4. John Bernard
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  5. Gillian Maughan
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  6. Francis P. Muldowney
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Freaney, R., O'Donohoe, P., Bergin, R. et al. Serum ionised calcium determination by ion specific electrode, and its value in clinical metabolic disorders. Ir J Med Sci 143, 286–295 (1974). https://doi.org/10.1007/BF03004777

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  • DOI: https://doi.org/10.1007/BF03004777

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