Summary
A method of local cerebral hypothermia has been used over the past nine years to mitigate the effects of cerebral ischaemia during carotid endarterectomy. Bradycardia, seen immediately after initiation of a 500 cc infusion of cold blood in the carotid artery, has been quite transient in duration. Atrio-ventricular conduction is prolonged, and periods of 15 seconds of asystole have been recorded. It would appear that the bradycardia is related to a sudden cerebral cold stimulus to the hypothalamus.
Résumé
Au cours des neuf dernières années, nous avons employé une méthode ďhypothermie cérébrale locale pour atténuer les effets de ľischémie cérébrale au cours de ľendartériectomie carotidienne. Dès le début de ľinfusion de 500 cc de sang froid dans ľartère carotidienne, il est apparu une bradycardie qui, toutefois, n’a été que transitoire. La conduction atrio-ventriculaire est ralentie et nous avons observé des périodes ďasystolie de 15 secondes. Selon toute apparence, le bradycardie est attribuable à une stimulation cérébrale soudaine par le froid au niveau de ľhypothalamus.
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This investigation was supported in part by nih Training Grant no. T12-GMO1835-01 from the National Institute of General Medical Sciences.
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Walker, R.L., Schlobohm, R.M., Cooke, F.N. et al. Bradycardia with carotid system infusions of cold blood during endarterectomy. Can. Anaesth. Soc. J. 17, 221–226 (1970). https://doi.org/10.1007/BF03004599
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DOI: https://doi.org/10.1007/BF03004599