Summary
The effects of electronarcosis on peripheral haemodynamics were studied in the isolated forelimb preparation of the dog. Forelimbs of dogs under nembutal anaesthesia were severed from the body and perfused at constant flow rate by a Sigma motor pump with blood drawn from animals under electronarcosis. It was found that blood from animals under electronarcosis consistently caused vasoconstriction in the isolated forelimb which could be blocked partially by phentolamine. It is concluded that electronarcosis causes the release of vasoactive substances into the circulation, the bulk of which appear to be catecholamines.
Résumé
On a étudié les effets de ľélectronarcose sur ľhémodynamique périphérique dans une préparation ďun membre antérieur de chien, préalablement séparé de ľanimal. Des membres antérieurs de chiens sous anesthésie au nembutal ont été séparés du corps et perfusés à courant constant, à ľaide ďune pompe à moteur Sigma, avec du sang ďanimaux sous électronarcose. On a trouvé que le sang ďanimaux sous électronarcose produisait constamment, dans le membre isolé, une vasoconstriction qui pouvait être partiellement contrô1ée par la Régitine. On en conclut que ľélectronarcose amène la libération de substance vasoactives dans la circulation; la plus grande partie de ces substances semble être des catécholamines.
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Received for publication August 1968.
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Massion, W.H., Downs, P. Peripheral haemodynamic effects of electronarcosis. Can. Anaes. Soc. J. 16, 302–308 (1969). https://doi.org/10.1007/BF03004458
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DOI: https://doi.org/10.1007/BF03004458