Conclusions
the incubation of powdered liver with injectable liver extract caused an activation, or perhaps formation, of a cholinesterase which had some of the properties of a specific cholinesterase. This was, in general, of the type found in red blood cells and in the central nervous system.
The incubation of powdered liver with pteroylglutamic acid activated, or created, mainly an activity which resembled the of a non-specific cholinesterase of the general type that is found in blood serum.
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References
Sabine, J. C., “Cholinesterase of Blood Cells and Plasma in Blood Dyscrasias with Special Reference to Pernicious Amemia.” J. Clin. Investig.,19, 833, 1940.
Meyer, L. M., Sawitsky, A., Ritz, N. D., and H. M. Fitch. “Cholinesterase Activity of the Blood of Patients with Pernicious Anemia.” J. Lab. & Clin. Med.,33, 189, 1948.
Davis, J. E., “Effect of Various Anti-anemic Substances on Serum Cholinesterase Activity.” Proc. Soc. Exper. Biol. & Med.,63, 287, 1946.
Davis, J. E., and Hamilton, W. M., “The Influence of Folic Acid on Serum Cholinesterase Activity in Human Subjects.” Fed. Proc.,6, 95, 1947.
Davis, J. E., “The Experimental Production of a Hyperchromic Anemia which is Responsive to Anti-Pernicious Anemia treatment.” Am. J. Physiol.,142, 402, 1944.
Davis, J. E., “Hyperchromic Ameia Produced by Choline or Acctylcholine and the Induced Remission of Both by Folic Acid or Liver Injection.” Am. J. Physiol.,147, 404, 1946.
Davis, J. E., “High Serum Acetylcholine Concentrations in Pernicious Anemia and Their Reduction by Effective Therapy.” Am. J. Dig. Diseases,15, 52, 1948.
Barnard, R. D. and Mentha, J. W., “Effect of a Cholinesterase-containing globulin Fraction of Human Plasma in Macrocytie Anemia.” Science,107, 195, 1948.
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Research paper no. 914, journal series, University of Arkansas. Laboratories.
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Davis, J.E. Anti-anemic agents and cholinesterase activity. Amer. Jour. Dig. Dis. 17, 339–340 (1950). https://doi.org/10.1007/BF03002585
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DOI: https://doi.org/10.1007/BF03002585