Summary and conclusions
The Takata-Ara test will be positive in slightly more than half of the cases in which there is parenchymatous hepatic damage when the injury has reached a moderately severe stage. The test is not specific for any one disease of the liver.
The test is correlated to a great extent with changes in the ratio of albumin to globulin, but the correlation is not an absolute one.
Although few false positive reactions are encountered, the test is not very sensitive.
The bromsulphalein test is highly specific in detecting that injury to the liver which results in its failure to excrete bilirubin properly.
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Crane, M. P.: A modified mercuric chlorid reaction (Takata-Ara) in cirrhosis and in neoplasms of the liver.Am. Jour. Med. Sc., 187:705–710, May, 1934.
van Ginkel, J. H. R.: Takata-Ara test in cirrhosis of liver.Nederl. Tijdschr. v. Geneesk., 78:991–996, 1934.
Heath, C. W.: Takata-Ara test in the diagnosis of liver disease.New England Jour. Med., 211:1077–1081, Dec. 13, 1934.
Jezler, Adolf: Die Takatasche Kolloidreaktion in Serum und Körperflüssigkeiten und ihre Beziehungen zu Störungen des Eiweisstoffwechsels der Leber.Ztschr. f. klin. Med., 114:739–756, 1930.
Pongor, F.: Uber die Takata-Reaktion.Beitr. z. Klin. d. Tuberk., 78:758–759, 1931.
Ragins, A. B.: The value of the Takata and Ara reaction as a diagnostic and prognostic aid in cirrhosis of the liver.Jour. Lab. and Clin. Med., 20:902–913, June, 1935.
Rohrer, Christian: Uber Takata-Ara-Reaktion (Modifikation Jezler) bei Leberaffektionen.Ztschr. f. klin. Med., 123:637–648, 1933.
Schindel, L., and Barth, E.: Die Bedeutung der Takata-Reaction für die Diagnose der Lebererkrankungen in ihrem Verhältnis zur Galaktose- und Bilirubin-Belastung.Klin. Wchnschr., 13:1355–1359, Sept. 22, 1934.
Takata, M.: Uber eine Kolloidchemische Sero-Diagnostik der Lungenentzündung. Tr. Sixth Congress Far Eastern Assn. Trop. Med., 1:693–699, 1925.
Takata, M., and Ara, K.: Uber eine neue Kolloidchemische Liquorreaktion und ihre Praktischen Ergebnisse. Tr. Sixth Congress Far Eastern Assn. Trop. Med., 1:667–671, 1925.
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Magath, T.B. The takata-ara test of liver function. American Journal of Digestive Diseases and Nutrition 2, 713–716 (1935). https://doi.org/10.1007/BF03002433
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DOI: https://doi.org/10.1007/BF03002433