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Experimental production of gastric ulcers in dogs by inducing vascular spasm with pitressin

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The American Journal of Digestive Diseases

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Authors and Affiliations

  1. College of Medicine, University of Illinois, Chicago, Illinois

    A. J. Nedzel

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  1. A. J. Nedzel
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Additional information

From the Department of Pathology, Bacteriology and Public Health in the College of Medicine, University of Illinois. This article is reprinted by permission from the book—Vascular Spasm by A. J. Nedzel, M.D., M.S. The University of Illinois Press, Urbana, Illinois, pp. 151, 1943. $2.75 cloth bound, $2.25 paper bound.

Editor’s Note: This article forms only one part of a series of experiments related to the effects of pitressin-induced vascular spasm in dogs. The author’s book, “Vascular Spasm” indicates that endocarditis and a disseminated sclerosis of the nervous tissue also can be produced by this method. The present article deals only with experimental production of gastric ulcers by this technique. Dr. Nedzel’s general thesis is rather iconoclastic, nevertheless, it is well supported by pathological findings and deserves careful consideration by all gastro-enterologists. The Journal is indebted to him and to the University of Illinois Press for permission to reprint this chapter, also for the use of the valuable copper engravings, which were loaned.

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Nedzel, A.J. Experimental production of gastric ulcers in dogs by inducing vascular spasm with pitressin. Jour. D. D. 10, 283–296 (1943). https://doi.org/10.1007/BF03002308

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