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The effect of tripelennamine hydrochloride (Pyribenzamine) on the gastric acidity of patients with peptic ulcer

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The American Journal of Digestive Diseases

Conclusions

Tripelennamine hydrochloride (pyribenzamine) has no significant effect either on the volume or the degree of acidity of the gastric juice in patients with peptic ulcer.

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References

  1. Edkins, J. S.: On the chemical mechanism of gastric secretion. Proc. Roy. Soc. London, 76:376, 1905. The chemical mechanism of gastric secretion. J. Physiol, 34:33, 1906.

    Article  Google Scholar 

  2. Best, C. H. and Taylor, N. B.: The physiological basis of medical practice, 4th edition, 1946. Wm. and Wilkins Co., Baltimore.

    Google Scholar 

  3. Portis, S. A.: Diseases of the digestive system, 2nd edition, 1944. Lea and Febiger, Philadelphia.

    Google Scholar 

  4. Edkins, J. S. and Tweedy, M.: The natural channels of absorption evoking the chemical mechanism of gastric secretion. J. Physiol. 38:263, 1909.

    PubMed  CAS  Google Scholar 

  5. Mayer, R. L.: Antihistamine substances, with special references to pyribenzamine. J. Allergy. 17:153, 1946.

    Article  CAS  Google Scholar 

  6. Loew, E. R., Kaiser, M. E. and Moore, V., Synthetic benzhydryl alkamine ethers effective in preventing fatal experimental asthma in guinea pigs exposed to atomized histamine. J. Pharmacol and Exper. Therap. 83:120, 1945.

    CAS  Google Scholar 

  7. Loew, E. R. and Kaiser, M. E., Alleviation of anaphylactic shock in guinea pigs with synthetic benzhydryl alkamine ethers. Proc. Soc. Exper. Biol. and Med. 58:235, 1945.

    CAS  Google Scholar 

  8. Feinberg, S. M.: Histamine and antihistaminic agents. Jour. Am. Med. Assn. 132:702, 1946.

    CAS  Google Scholar 

  9. McGavack, T. H., Elias, H. and Boyd, L. J.: Some pharmacological and clinical experiences with dimethylaminoethyl benzhydryl ether hydrochloride (Benadryl). Am. J. Med. Sci. 213:418, 1947.

    Article  CAS  Google Scholar 

  10. McGavack, T. H., Elias H. and Boyd, L. J.: Influence of benadryl (Dimethylaminoethylbenzhydryl ether hydrochloride) on gastric acidity. Gastroenterology. 6:439, 1946.

    CAS  Google Scholar 

  11. McGavack, T. H., Elias, H. and Boyd, L. J.: The influence of dimethylaminoethyl benzhydryl ether hydrochloride (Benadryl) upon normal persons and upon those suffering from disturbances of the autonomic nervous system. J. Lab and Clin. Med. 31:560, 1946.

    CAS  Google Scholar 

  12. Crane, J. T., Lindsey, S. and Dailey, M. E.: An attempt to prevent histamine-induced ulcers in guinea pigs with benadryl. Am. J. Dig. Dis. 14:56, 1947.

    CAS  Google Scholar 

  13. Loveless, M. H.: Therapeutic and side effects of pyribenzamine and benadryl. Am. J. Med. 3:296, 1947.

    Article  Google Scholar 

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Authors and Affiliations

  1. From the Medical Service, Veteran’s Administration Hospital, and the Department of Medicine, University of Utah Medical School, Salt Lake City, Utah.

    Seymour A. Hartman M.D. & Donald M. Moore M.D.

Authors
  1. Seymour A. Hartman M.D.
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  2. Donald M. Moore M.D.
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Hartman, S.A., Moore, D.M. The effect of tripelennamine hydrochloride (Pyribenzamine) on the gastric acidity of patients with peptic ulcer. A. J. D. D. 15, 271–275 (1948). https://doi.org/10.1007/BF03001582

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  • DOI: https://doi.org/10.1007/BF03001582

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