Summary
Colloidal aluminum hydroxide gel and magnesium hydroxide combination is an effective stable buffer which acts in the stomach for several hours. With this combination ulcer pain and heartburn may be controlled with smaller and less frequent doses than are required with the colloidal aluminum hydroxide gel alone. Clinically it can be continued for long periods without the danger of an acid rebound, alkalosis or aggravation of constipation.
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Jankelson, I.R. Colloidal aluminum hydroxidel gel and magnesium hydroxide in the management of peptic ulcers. Jour. D. D. 14, 11–12 (1947). https://doi.org/10.1007/BF03001254
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DOI: https://doi.org/10.1007/BF03001254